HHIP - Revision history

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← Previous revision		Revision as of 02:06, 1 December 2023
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	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}
	*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}		*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 \|doi-access=free }}
	*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}		*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}
	*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 \|s2cid=85407133 }}		*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 \|s2cid=85407133 }}

Ffffrr: Importing Wikidata short description: "Protein-coding gene in the species Homo sapiens"

2022-10-28T03:39:47Z

Importing Wikidata short description: "Protein-coding gene in the species Homo sapiens"

← Previous revision		Revision as of 03:39, 28 October 2022
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			{{Short description\|Protein-coding gene in the species Homo sapiens}}
	{{Infobox_gene}}		{{Infobox_gene}}
	'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| doi =10.1159/000056918 \| s2cid = 32938414 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399}}</ref>		'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| doi =10.1159/000056918 \| s2cid = 32938414 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399}}</ref>

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← Previous revision		Revision as of 06:40, 13 October 2022
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	==Further reading==		==Further reading==
	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}		*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|bibcode=1999Natur.397..617C \|s2cid=204991314 }}
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|doi-access=free }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|bibcode=2002PNAS...9916899M \|doi-access=free }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}

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2021-08-31T14:45:41Z

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← Previous revision		Revision as of 14:45, 31 August 2021
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	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}		*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|doi-access=free }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}

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2020-12-15T04:59:44Z

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← Previous revision		Revision as of 04:59, 15 December 2020
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 ~~\| pmc =~~ \| doi =10.1159/000056918 \| s2cid = 32938414 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 ~~\| pmc =~~ \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399~~\| accessdate =~~ }}</ref>		'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| doi =10.1159/000056918 \| s2cid = 32938414 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399}}</ref>

	This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>		This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>

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2020-10-11T08:09:36Z

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← Previous revision		Revision as of 08:09, 11 October 2020
Line 1:		Line 1:
	{{Infobox_gene}}		{{Infobox_gene}}
	'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>		'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 \| s2cid = 32938414 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>

	This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>		This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>
Line 9:		Line 9:
	==Further reading==		==Further reading==
	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 }}		*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
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	*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}		*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}
	*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}		*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}
	*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}		*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 \|s2cid=85407133 }}
	*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802\|doi-access=free }}		*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802\|doi-access=free }}
	{{refend}}		{{refend}}

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2020-04-11T21:39:05Z

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← Previous revision		Revision as of 21:39, 11 April 2020
Line 1:		Line 1:
	{{Infobox_gene}}		{{Infobox_gene}}
	'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>		'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>

	This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>		This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>
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	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}
	*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}		*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}
	*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}		*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}
	*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}		*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}
	*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802}}		*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802\|doi-access=free }}
	{{refend}}		{{refend}}

Zackmann08: removing template per Wikipedia:Templates_for_discussion/Log/2019_March_9#Template:PBB_Controls

2019-03-20T21:16:05Z

removing template per Wikipedia:Templates_for_discussion/Log/2019_March_9#Template:PBB_Controls

← Previous revision		Revision as of 21:16, 20 March 2019
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	==Further reading==		==Further reading==
	{{refbegin \| 2}}		{{refbegin \| 2}}
	{{PBB_Further_reading
	\| citations =
	*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 }}		*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 }}
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}
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	*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}		*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}
	*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802}}		*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802}}
	}}
	{{refend}}		{{refend}}

DannyS712 bot: /* Further reading */Task 22: Remove Template:PBB Controls per TfD

2019-03-20T18:01:36Z

Further reading: Task 22: Remove Template:PBB Controls per TfD

← Previous revision		Revision as of 18:01, 20 March 2019
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	{{refend}}		{{refend}}

	<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
	{{PBB_Controls
	\| update_page = yes
	\| require_manual_inspection = no
	\| update_protein_box = yes
	\| update_summary = no
	\| update_citations = yes
	}}
	{{Hedgehog signaling pathway}}		{{Hedgehog signaling pathway}}

KolbertBot: Bot: HTTP→HTTPS

2017-08-31T13:35:30Z

Bot: HTTP→HTTPS

← Previous revision		Revision as of 13:35, 31 August 2017
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = ~~http~~://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>		'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>

	This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>		This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>

← Previous revision		Revision as of 02:06, 1 December 2023
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	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}
	*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}		*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 \|doi-access=free }}
	*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}		*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}
	*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 \|s2cid=85407133 }}		*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 \|s2cid=85407133 }}

← Previous revision		Revision as of 06:40, 13 October 2022
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	==Further reading==		==Further reading==
	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}		*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|bibcode=1999Natur.397..617C \|s2cid=204991314 }}
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|doi-access=free }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|bibcode=2002PNAS...9916899M \|doi-access=free }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}

← Previous revision		Revision as of 14:45, 31 August 2021
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	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}		*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|doi-access=free }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}

← Previous revision		Revision as of 08:09, 11 October 2020
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>		'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 \| s2cid = 32938414 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>

	This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>		This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>
Line 9:		Line 9:
	==Further reading==		==Further reading==
	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 }}		*{{cite journal \|vauthors=Chuang PT, McMahon AP \|title=Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein \|journal=Nature \|volume=397 \|issue= 6720 \|pages= 617–21 \|year= 1999 \|pmid= 10050855 \|doi= 10.1038/17611 \|s2cid=204991314 }}
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
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	*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}		*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}
	*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}		*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}
	*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}		*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 \|s2cid=85407133 }}
	*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802\|doi-access=free }}		*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802\|doi-access=free }}
	{{refend}}		{{refend}}

← Previous revision		Revision as of 21:39, 11 April 2020
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>		'''Hedgehog interacting protein''' ('''HHIP''') is a [[protein]] that in humans is encoded by the ''HHIP'' [[gene]].<ref name="pmid11435703">{{cite journal \|vauthors=Bak M, Hansen C, Friis Henriksen K, Tommerup N \| title = The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3 \| journal = Cytogenet Cell Genet \| volume = 92 \| issue = 3–4 \| pages = 300–3 \|date=Jul 2001 \| pmid = 11435703 \| pmc = \| doi =10.1159/000056918 }}</ref><ref name="pmid11731473">{{cite journal \|vauthors=Ingham PW, McMahon AP \| title = Hedgehog signaling in animal development: paradigms and principles \| journal = Genes Dev \| volume = 15 \| issue = 23 \| pages = 3059–87 \|date=Dec 2001 \| pmid = 11731473 \| pmc = \| doi = 10.1101/gad.938601 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: HHIP hedgehog interacting protein\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64399\| accessdate = }}</ref>

	This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>		This gene encodes a [[protein]] similar to the mouse hedgehog interacting protein, a regulatory component of the [[Hedgehog signaling pathway]]. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic [[developmental biology\|development]], including [[anteroposterior#Anterior and posterior\|anteroposterior]] patterns of limbs and regulation of left-right asymmetry.<ref name="entrez"/>
Line 12:		Line 12:
	*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}		*{{cite journal \|vauthors=Strausberg RL, Feingold EA, Grouse LH, etal \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 }}
	*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}		*{{cite journal \|vauthors=Clark HF, Gurney AL, Abaya E, etal \|title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment \|journal=Genome Res. \|volume=13 \|issue= 10 \|pages= 2265–70 \|year= 2003 \|pmid= 12975309 \|doi= 10.1101/gr.1293003 \| pmc=403697 }}
	*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 }}		*{{cite journal \|vauthors=Ota T, Suzuki Y, Nishikawa T, etal \|title=Complete sequencing and characterization of 21,243 full-length human cDNAs \|journal=Nat. Genet. \|volume=36 \|issue= 1 \|pages= 40–5 \|year= 2004 \|pmid= 14702039 \|doi= 10.1038/ng1285 \|doi-access= free }}
	*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}		*{{cite journal \|vauthors=Olsen CL, Hsu PP, Glienke J, etal \|title=Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors \|journal=BMC Cancer \|volume=4\|pages= 43 \|year= 2004 \|pmid= 15294024 \|doi= 10.1186/1471-2407-4-43 \| pmc=512291 }}
	*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}		*{{cite journal \|vauthors=Gerhard DS, Wagner L, Feingold EA, etal \|title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 }}
	*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}		*{{cite journal \|vauthors=Kayed H, Kleeff J, Esposito I, etal \|title=Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas \|journal=Mol. Carcinog. \|volume=42 \|issue= 4 \|pages= 183–92 \|year= 2005 \|pmid= 15754313 \|doi= 10.1002/mc.20088 }}
	*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802}}		*{{cite journal \|vauthors=Martin ST, Sato N, Dhara S, etal \|title=Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms \|journal=Cancer Biol. Ther. \|volume=4 \|issue= 7 \|pages= 728–33 \|year= 2006 \|pmid= 15970691 \|doi= 10.4161/cbt.4.7.1802\|doi-access=free }}
	{{refend}}		{{refend}}