Phenazepam - Revision history

76.174.0.57: See also.

2024-10-08T02:02:25Z

QFFlyer: Legal status for Australia - two entries stating "Unscheduled" and "S8" both incorrect; updated to reflect current Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP).

2024-09-19T04:34:23Z

Legal status for Australia - two entries stating "Unscheduled" and "S8" both incorrect; updated to reflect current Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP).

← Previous revision		Revision as of 04:34, 19 September 2024
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	\| legal_BR = B1		\| legal_BR = B1
	\| legal_BR_comment = <ref>{{Cite web \|author=Anvisa \|author-link=Brazilian Health Regulatory Agency \|date=2023-03-31 \|title=RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial \|trans-title=Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control\|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|url-status=live \|archive-url=https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|archive-date=2023-08-03 \|access-date=2023-08-16 \|publisher=[[Diário Oficial da União]] \|language=pt-BR \|publication-date=2023-04-04}}</ref>		\| legal_BR_comment = <ref>{{Cite web \|author=Anvisa \|author-link=Brazilian Health Regulatory Agency \|date=2023-03-31 \|title=RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial \|trans-title=Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control\|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|url-status=live \|archive-url=https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|archive-date=2023-08-03 \|access-date=2023-08-16 \|publisher=[[Diário Oficial da União]] \|language=pt-BR \|publication-date=2023-04-04}}</ref>
	\| legal_AU. = S8
	\| legal_CA = Schedule IV		\| legal_CA = Schedule IV
	\| legal_DE = NPSG		\| legal_DE = NPSG
	\| legal_UK = Class C		\| legal_UK = Class C
			\| legal_AU = S4 (Prescription Only Medicine) - Not specifically scheduled by name in SUSMP, but would be covered by the catch all of "Benzodiazepine Derivatives except where separately specified" listed in Schedule 4.<ref>{{cite web \|url=https://www.legislation.gov.au/F2024L00589/asmade/2024-05-30/text/original/epub/OEBPS/document_1/document_1.html#_Toc153874658\|title = Therapeutic Goods (Poisons Standard—June 2024) Instrument 2024}}</ref>
	\| legal_AU = Unscheduled
	\| legal_US = Unscheduled (Schedule I in Louisiana).<ref>{{cite web \|url=http://www.legis.la.gov/legis/Law.aspx?d=98877\|title = Louisiana Laws - Louisiana State Legislature}}</ref> Not FDA approved.		\| legal_US = Unscheduled (Schedule I in Louisiana).<ref>{{cite web \|url=http://www.legis.la.gov/legis/Law.aspx?d=98877\|title = Louisiana Laws - Louisiana State Legislature}}</ref> Not FDA approved.
	\| legal_status = <small>([[Russian Federation\|RU]])</small> Rx only <ref>http://pravo.gov.ru/proxy/ips/?docbody=&nd=102119239 = СПИСОК		\| legal_status = <small>([[Russian Federation\|RU]])</small> Rx only <ref>http://pravo.gov.ru/proxy/ips/?docbody=&nd=102119239 = СПИСОК

JWBE: removed Category:4-Chlorophenyl compounds; added Category:2-Chlorophenyl compounds using HotCat

2024-09-07T16:12:15Z

removed Category:4-Chlorophenyl compounds; added Category:2-Chlorophenyl compounds using HotCat

← Previous revision		Revision as of 16:12, 7 September 2024
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	[[Category:Benzodiazepines]]		[[Category:Benzodiazepines]]
	[[Category:4-Chlorophenyl compounds]]		[[Category:2-Chlorophenyl compounds]]
	[[Category:Bromobenzene derivatives]]		[[Category:Bromobenzene derivatives]]
	[[Category:Lactams]]		[[Category:Lactams]]

JWBE: removed Category:Chlorobenzene derivatives; added Category:4-Chlorophenyl compounds using HotCat

2024-09-07T16:12:00Z

removed Category:Chlorobenzene derivatives; added Category:4-Chlorophenyl compounds using HotCat

← Previous revision		Revision as of 16:12, 7 September 2024
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	[[Category:Benzodiazepines]]		[[Category:Benzodiazepines]]
	[[Category:~~Chlorobenzene~~ ~~derivatives~~]]		[[Category:4-Chlorophenyl compounds]]
	[[Category:Bromobenzene derivatives]]		[[Category:Bromobenzene derivatives]]
	[[Category:Lactams]]		[[Category:Lactams]]

Citation bot: Altered journal. | Use this bot. Report bugs. | Suggested by Grimes2 | #UCB_webform 555/1378

2024-08-24T14:29:18Z

Altered journal. | Use this bot. Report bugs. | Suggested by Grimes2 | #UCB_webform 555/1378

← Previous revision		Revision as of 14:29, 24 August 2024
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	<!--Pharmacokinetic data-->\| bioavailability = 16,7% (rat)<ref>{{cite thesis\|title=Pharmacokinetics of Transdermal therapeutic Systems of Phenazepam and Cytisine in the Experiment (abstract)\|url=http://www.dissercat.com/content/farmakokinetika-transdermalnykh-terapevticheskikh-sistem-fenazepama-i-tsitizina-v-eksperimen\|website=DisserCat — Electronic Library of Dissertations\|year=1999\|language=ru}}</ref>		<!--Pharmacokinetic data-->\| bioavailability = 16,7% (rat)<ref>{{cite thesis\|title=Pharmacokinetics of Transdermal therapeutic Systems of Phenazepam and Cytisine in the Experiment (abstract)\|url=http://www.dissercat.com/content/farmakokinetika-transdermalnykh-terapevticheskikh-sistem-fenazepama-i-tsitizina-v-eksperimen\|website=DisserCat — Electronic Library of Dissertations\|year=1999\|language=ru}}</ref>
	\| metabolism = [[Liver\|Hepatic]] — [[Aromaticity\|aromatic]] oxidation and C3-[[hydroxylation]]<ref>{{cite journal \| vauthors = Golovenko NI, Zin'kovskiĭ VG \| title = [2-14C-phenazepam metabolism in vitro] \| language = ru \| journal = Farmakologiia I Toksikologiia \| volume = 42 \| issue = 6 \| pages = 597–600 \| date = 1979 \| pmid = 40817 }}</ref>		\| metabolism = [[Liver\|Hepatic]] — [[Aromaticity\|aromatic]] oxidation and C3-[[hydroxylation]]<ref>{{cite journal \| vauthors = Golovenko NI, Zin'kovskiĭ VG \| title = [2-14C-phenazepam metabolism in vitro] \| language = ru \| journal = Farmakologiia i Toksikologiia \| volume = 42 \| issue = 6 \| pages = 597–600 \| date = 1979 \| pmid = 40817 }}</ref>
	\| onset = 1.5–4 hours		\| onset = 1.5–4 hours
	\| elimination_half-life = 6–18 hours (active metabolite unknown)		\| elimination_half-life = 6–18 hours (active metabolite unknown)

Qwerfjkl: Added 1 {{Bare URL PDF}} tag(s) using a script. For other recently-tagged pages with bare URLs, see :Category:Articles with bare URLs for citations from August 2024 and :Category:Articles with PDF format bare URLs for citations

2024-08-17T20:16:55Z

Added 1 {{Bare URL PDF}} tag(s) using a script. For other recently-tagged pages with bare URLs, see Category:Articles with bare URLs for citations from August 2024 and Category:Articles with PDF format bare URLs for citations

← Previous revision		Revision as of 20:16, 17 August 2024
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	Paul Halverson, director and state health officer for the Arkansas Department of Health, approved an emergency rule to ban the sale and distribution of phenazepam shortly after the Louisiana ban.		Paul Halverson, director and state health officer for the Arkansas Department of Health, approved an emergency rule to ban the sale and distribution of phenazepam shortly after the Louisiana ban.

	[[Alabama]] made Phenazepam a schedule I substance on March 18th, 2014.<ref>https://www.alabamapublichealth.gov/blog/assets/controlledsubstanceslist.pdf</ref>		[[Alabama]] made Phenazepam a schedule I substance on March 18th, 2014.<ref>https://www.alabamapublichealth.gov/blog/assets/controlledsubstanceslist.pdf {{Bare URL PDF\|date=August 2024}}</ref>

	===United Kingdom===		===United Kingdom===

Gettinglit: /* United States */

2024-08-09T00:15:25Z

United States

← Previous revision		Revision as of 00:15, 9 August 2024
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	Paul Halverson, director and state health officer for the Arkansas Department of Health, approved an emergency rule to ban the sale and distribution of phenazepam shortly after the Louisiana ban.		Paul Halverson, director and state health officer for the Arkansas Department of Health, approved an emergency rule to ban the sale and distribution of phenazepam shortly after the Louisiana ban.

			[[Alabama]] made Phenazepam a schedule I substance on March 18th, 2014.<ref>https://www.alabamapublichealth.gov/blog/assets/controlledsubstanceslist.pdf</ref>

	===United Kingdom===		===United Kingdom===

2800:200:F540:251C:315D:22A8:415A:6BE1: Fixed typo

2024-08-05T05:05:32Z

Fixed typo

← Previous revision		Revision as of 05:05, 5 August 2024
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	\| legal_BR = B1		\| legal_BR = B1
	\| legal_BR_comment = <ref>{{Cite web \|author=Anvisa \|author-link=Brazilian Health Regulatory Agency \|date=2023-03-31 \|title=RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial \|trans-title=Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control\|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|url-status=live \|archive-url=https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|archive-date=2023-08-03 \|access-date=2023-08-16 \|publisher=[[Diário Oficial da União]] \|language=pt-BR \|publication-date=2023-04-04}}</ref>		\| legal_BR_comment = <ref>{{Cite web \|author=Anvisa \|author-link=Brazilian Health Regulatory Agency \|date=2023-03-31 \|title=RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial \|trans-title=Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control\|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|url-status=live \|archive-url=https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|archive-date=2023-08-03 \|access-date=2023-08-16 \|publisher=[[Diário Oficial da União]] \|language=pt-BR \|publication-date=2023-04-04}}</ref>
			\| legal_AU. = S8
	\| legal_CA = Schedule IV		\| legal_CA = Schedule IV
	\| legal_DE = NPSG		\| legal_DE = NPSG
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	\| legal_AU = Unscheduled		\| legal_AU = Unscheduled
	\| legal_US = Unscheduled (Schedule I in Louisiana).<ref>{{cite web \|url=http://www.legis.la.gov/legis/Law.aspx?d=98877\|title = Louisiana Laws - Louisiana State Legislature}}</ref> Not FDA approved.		\| legal_US = Unscheduled (Schedule I in Louisiana).<ref>{{cite web \|url=http://www.legis.la.gov/legis/Law.aspx?d=98877\|title = Louisiana Laws - Louisiana State Legislature}}</ref> Not FDA approved.
	\| legal_status = <small>([[Russian Federation\|RU]])</small Rx only <ref>http://pravo.gov.ru/proxy/ips/?docbody=&nd=102119239 = СПИСОК		\| legal_status = <small>([[Russian Federation\|RU]])</small> Rx only <ref>http://pravo.gov.ru/proxy/ips/?docbody=&nd=102119239 = СПИСОК
	сильнодействующих веществ для целей статьи 234 и других статей Уголовного кодекса Российской Федерации \|</ref>		сильнодействующих веществ для целей статьи 234 и других статей Уголовного кодекса Российской Федерации \|</ref>
	\| routes_of_administration = Oral, [[Intramuscular injection\|IM]], [[Intravenous therapy\|IV]]		\| routes_of_administration = Oral, [[Intramuscular injection\|IM]], [[Intravenous therapy\|IV]]

2800:200:F540:251C:315D:22A8:415A:6BE1: Fixed typo, added content

2024-08-05T04:50:19Z

Fixed typo, added content

← Previous revision		Revision as of 04:50, 5 August 2024
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	\| legal_BR_comment = <ref>{{Cite web \|author=Anvisa \|author-link=Brazilian Health Regulatory Agency \|date=2023-03-31 \|title=RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial \|trans-title=Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control\|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|url-status=live \|archive-url=https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|archive-date=2023-08-03 \|access-date=2023-08-16 \|publisher=[[Diário Oficial da União]] \|language=pt-BR \|publication-date=2023-04-04}}</ref>		\| legal_BR_comment = <ref>{{Cite web \|author=Anvisa \|author-link=Brazilian Health Regulatory Agency \|date=2023-03-31 \|title=RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial \|trans-title=Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control\|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|url-status=live \|archive-url=https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 \|archive-date=2023-08-03 \|access-date=2023-08-16 \|publisher=[[Diário Oficial da União]] \|language=pt-BR \|publication-date=2023-04-04}}</ref>
	\| legal_CA = Schedule IV		\| legal_CA = Schedule IV
	\| legal_DE = ~~Anlage III~~		\| legal_DE = NPSG
	\| legal_UK = Class C		\| legal_UK = Class C
	\| legal_AU =		\| legal_AU = Unscheduled
	\| legal_US = Schedule I in Louisiana.<ref>{{cite web \|url=http://www.legis.la.gov/legis/Law.aspx?d=98877\|title = Louisiana Laws - Louisiana State Legislature}}</ref> Not FDA approved.		\| legal_US = Unscheduled (Schedule I in Louisiana).<ref>{{cite web \|url=http://www.legis.la.gov/legis/Law.aspx?d=98877\|title = Louisiana Laws - Louisiana State Legislature}}</ref> Not FDA approved.
	\| legal_status = <small>([[Russian Federation\|RU]])</small>: ~~Schedule~~ of		\| legal_status = <small>([[Russian Federation\|RU]])</small Rx only <ref>http://pravo.gov.ru/proxy/ips/?docbody=&nd=102119239 = СПИСОК
	potent and toxic substances <ref>http://pravo.gov.ru/proxy/ips/?docbody=&nd=102119239 = СПИСОК
	сильнодействующих веществ для целей статьи 234 и других статей Уголовного кодекса Российской Федерации \|</ref>		сильнодействующих веществ для целей статьи 234 и других статей Уголовного кодекса Российской Федерации \|</ref>
	\| routes_of_administration = Oral, [[Intramuscular injection\|IM]], [[Intravenous therapy\|IV]]		\| routes_of_administration = Oral, [[Intramuscular injection\|IM]], [[Intravenous therapy\|IV]]

94.255.152.53: alcohol (drug)|alcohol

2024-06-06T00:28:18Z

alcohol (drug)|alcohol

← Previous revision		Revision as of 00:28, 6 June 2024
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	Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, alcohol or drug-dependent individuals and individuals with [[comorbid]] [[psychiatric disorders]].<ref>{{cite journal \| vauthors = Authier N, Balayssac D, Sautereau M, Zangarelli A, Courty P, Somogyi AA, Vennat B, Llorca PM, Eschalier A \| display-authors = 6 \| title = Benzodiazepine dependence: focus on withdrawal syndrome \| journal = Annales Pharmaceutiques Françaises \| volume = 67 \| issue = 6 \| pages = 408–13 \| date = November 2009 \| pmid = 19900604 \| doi = 10.1016/j.pharma.2009.07.001 }}</ref>		Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, alcohol or drug-dependent individuals and individuals with [[comorbid]] [[psychiatric disorders]].<ref>{{cite journal \| vauthors = Authier N, Balayssac D, Sautereau M, Zangarelli A, Courty P, Somogyi AA, Vennat B, Llorca PM, Eschalier A \| display-authors = 6 \| title = Benzodiazepine dependence: focus on withdrawal syndrome \| journal = Annales Pharmaceutiques Françaises \| volume = 67 \| issue = 6 \| pages = 408–13 \| date = November 2009 \| pmid = 19900604 \| doi = 10.1016/j.pharma.2009.07.001 }}</ref>

	Phenazepam should not be taken with alcohol or any other CNS depressants. Phenazepam should not be used therapeutically for periods of longer than one month including tapering on and off the drug as recommended for any benzodiazepine in the British national formulary. Some patients may require longer term treatment.		Phenazepam should not be taken with [[alcohol (drug)\|alcohol]] or any other CNS depressants. Phenazepam should not be used therapeutically for periods of longer than one month including tapering on and off the drug as recommended for any benzodiazepine in the British national formulary. Some patients may require longer term treatment.

	Phenazepam was found to be a component in some "herbal incense" mixtures in Australia and New Zealand in 2011, namely "Kronic". The particular product variety was withdrawn from the market shortly after and replaced with a new formulation.<ref>{{cite journal \| vauthors = Couch RA, Madhavaram H \| title = Phenazepam and cannabinomimetics sold as herbal highs in New Zealand \| journal = Drug Testing and Analysis \| volume = 4 \| issue = 6 \| pages = 409–14 \| date = June 2012 \| pmid = 22924168 \| doi = 10.1002/dta.349 }}</ref>		Phenazepam was found to be a component in some "herbal incense" mixtures in Australia and New Zealand in 2011, namely "Kronic". The particular product variety was withdrawn from the market shortly after and replaced with a new formulation.<ref>{{cite journal \| vauthors = Couch RA, Madhavaram H \| title = Phenazepam and cannabinomimetics sold as herbal highs in New Zealand \| journal = Drug Testing and Analysis \| volume = 4 \| issue = 6 \| pages = 409–14 \| date = June 2012 \| pmid = 22924168 \| doi = 10.1002/dta.349 }}</ref>

← Previous revision		Revision as of 02:02, 8 October 2024
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	*[[Flubromazepam]]		*[[Flubromazepam]]
	*[[Ro07-9749]]		*[[Ro07-9749]]
			* [[List of Russian drugs]]

	== References ==		== References ==