THRSP - Revision history

1234qwer1234qwer4: Importing Wikidata short description: Protein-coding gene in the species Homo sapiens (shortdescs-in-category)

2023-03-04T00:52:53Z

Importing Wikidata short description: Protein-coding gene in the species Homo sapiens (shortdescs-in-category)

← Previous revision		Revision as of 00:52, 4 March 2023
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			{{Short description\|Protein-coding gene in the species Homo sapiens}}
	{{Infobox_gene}}		{{Infobox_gene}}
	'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069}}</ref>		'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069}}</ref>

Citation bot: Add: doi-access. | Use this bot. Report bugs. | Suggested by Headbomb | Linked from Wikipedia:WikiProject_Academic_Journals/Journals_cited_by_Wikipedia/Sandbox | #UCB_webform_linked 182/1049

2021-09-21T18:20:46Z

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← Previous revision		Revision as of 18:20, 21 September 2021
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	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-style=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-style=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-style=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-style=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M \|doi-access=free }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-style=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-style=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M \|doi-access=free }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-style=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-style=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}

OAbot: Open access bot: doi added to citation with #oabot.

2021-01-02T22:07:31Z

Open access bot: doi added to citation with #oabot.

← Previous revision		Revision as of 22:07, 2 January 2021
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069}}</ref>		'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 \| doi-access = free }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069}}</ref>

	The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.		The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.

Monkbot: Task 18 (cosmetic): eval 15 templates: del empty params (2×);

2020-12-17T10:19:53Z

Task 18 (cosmetic): eval 15 templates: del empty params (2×);

← Previous revision		Revision as of 10:19, 17 December 2020
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 ~~\| pmc =~~ \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069~~\| accessdate =~~ }}</ref>		'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069}}</ref>

	The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.		The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.

Monkbot: /* Further reading */Task 17 (BRFA trial): replace to-be-deprecated: |name-list-format= (7× replaced; usage: 7 of 9);

2020-10-20T07:24:48Z

Further reading: Task 17 (BRFA trial): replace to-be-deprecated: |name-list-format= (7× replaced; usage: 7 of 9);

← Previous revision		Revision as of 07:24, 20 October 2020
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	*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}		*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}
	*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 \|s2cid=22056127 }}		*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 \|s2cid=22056127 }}
	*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-~~format~~=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}		*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-style=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}
	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-~~format~~=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-style=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-~~format~~=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-style=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-~~format~~=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-style=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-~~format~~=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-style=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}
	*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-~~format~~=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R \|s2cid=4427026 }}		*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-style=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R \|s2cid=4427026 }}
	*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-~~format~~=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}		*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-style=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}
	{{refend}}		{{refend}}

Citation bot: Add: s2cid, author pars. 1-1. Removed parameters. Some additions/deletions were actually parameter name changes. | You can use this bot yourself. Report bugs here. | Suggested by Abductive | Category:Genes on human chromosome 11 | via #UCB_Category

2020-10-11T10:14:44Z

Add: s2cid, author pars. 1-1. Removed parameters. Some additions/deletions were actually parameter name changes. | You can use this bot yourself. Report bugs here. | Suggested by Abductive | Category:Genes on human chromosome 11 | via #UCB_Category

← Previous revision		Revision as of 10:14, 11 October 2020
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| pmc = \| doi =10.1016/S0014-5793(96)01433-0 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069\| accessdate = }}</ref>		'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| pmc = \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069\| accessdate = }}</ref>

	The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.		The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.
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	This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />		This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />

	Previously, THRSP was among the identified upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|~~last~~=dela Peña\|~~first~~=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012\|pmid=26048425}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|~~last~~=Custodio\|~~first~~=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008\|pmid=30138648}}</ref>		Previously, THRSP was among the identified upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|last1=dela Peña\|first1=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012\|pmid=26048425\|s2cid=9853684}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|last1=Custodio\|first1=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008\|pmid=30138648\|s2cid=52075574}}</ref>

	==References==		==References==
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	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}		*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}
	*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 }}		*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 \|s2cid=22056127 }}
	*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-format=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}		*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-format=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}
	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
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	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}
	*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R }}		*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R \|s2cid=4427026 }}
	*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-format=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}		*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-format=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}
	{{refend}}		{{refend}}

Rjwilmsi: /* Further reading */Journal cites:, added 1 Bibcode

2020-05-30T09:09:10Z

Further reading: Journal cites:, added 1 Bibcode

← Previous revision		Revision as of 09:09, 30 May 2020
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	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}

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← Previous revision		Revision as of 22:34, 17 April 2020
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	*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-format=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}		*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-format=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}
	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}
	*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija }}		*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija }}

Rjampc at 09:08, 22 March 2020

2020-03-22T09:08:43Z

← Previous revision		Revision as of 09:08, 22 March 2020
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	This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />		This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />

	Previously, THRSP was among the identified upregulated genes in spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|last=dela Peña\|first=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior\|url=https://linkinghub.elsevier.com/retrieve/pii/S0166432815003411\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|last=Custodio\|first=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice\|url=https://linkinghub.elsevier.com/retrieve/pii/S0306452218305463\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008}}</ref>		Previously, THRSP was among the identified upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|last=dela Peña\|first=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior\|url=https://linkinghub.elsevier.com/retrieve/pii/S0166432815003411\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|last=Custodio\|first=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice\|url=https://linkinghub.elsevier.com/retrieve/pii/S0306452218305463\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008}}</ref>

	==References==		==References==

← Previous revision		Revision as of 18:20, 21 September 2021
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	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-style=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-style=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-style=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-style=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M \|doi-access=free }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-style=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-style=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M \|doi-access=free }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-style=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-style=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}

← Previous revision		Revision as of 07:24, 20 October 2020
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	*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}		*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}
	*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 \|s2cid=22056127 }}		*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 \|s2cid=22056127 }}
	*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-~~format~~=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}		*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-style=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}
	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-~~format~~=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-style=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-~~format~~=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-style=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-~~format~~=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-style=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-~~format~~=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-style=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}
	*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-~~format~~=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R \|s2cid=4427026 }}		*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-style=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R \|s2cid=4427026 }}
	*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-~~format~~=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}		*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-style=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}
	{{refend}}		{{refend}}

← Previous revision		Revision as of 10:14, 11 October 2020
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	{{Infobox_gene}}		{{Infobox_gene}}
	'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| pmc = \| doi =10.1016/S0014-5793(96)01433-0 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069\| accessdate = }}</ref>		'''Thyroid hormone-inducible hepatic protein''' is a [[protein]] that in humans is encoded by the ''THRSP'' [[gene]].<ref name="pmid9003802">{{cite journal \|vauthors=Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R \| title = Cloning and initial characterization of human and mouse Spot 14 genes \| journal = FEBS Lett \| volume = 401 \| issue = 1 \| pages = 38–42 \|date=Feb 1997 \| pmid = 9003802 \| pmc = \| doi =10.1016/S0014-5793(96)01433-0 \| s2cid = 44575293 }}</ref><ref name="entrez">{{cite web \| title = Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)\| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7069\| accessdate = }}</ref>

	The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.		The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to [[liver]] and [[adipose tissue]] and is controlled by nutritional and hormonal factors.
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	This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />		This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />

	Previously, THRSP was among the identified upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|~~last~~=dela Peña\|~~first~~=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012\|pmid=26048425}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|~~last~~=Custodio\|~~first~~=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008\|pmid=30138648}}</ref>		Previously, THRSP was among the identified upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|last1=dela Peña\|first1=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012\|pmid=26048425\|s2cid=9853684}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|last1=Custodio\|first1=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008\|pmid=30138648\|s2cid=52075574}}</ref>

	==References==		==References==
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	{{refbegin \| 2}}		{{refbegin \| 2}}
	*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}		*{{cite journal \|vauthors=Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB \|title="Spot 14" protein: a metabolic integrator in normal and neoplastic cells. \|journal=Thyroid \|volume=8 \|issue= 9 \|pages= 815–25 \|year= 1998 \|pmid= 9777755 \|doi=10.1089/thy.1998.8.815 }}
	*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 }}		*{{cite journal \|vauthors=Ota Y, Mariash A, Wagner JL, Mariash CN \|title=Cloning, expression and regulation of the human S14 gene. \|journal=Mol. Cell. Endocrinol. \|volume=126 \|issue= 1 \|pages= 75–81 \|year= 1997 \|pmid= 9027365 \|doi=10.1016/S0303-7207(96)03971-8 \|s2cid=22056127 }}
	*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-format=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}		*{{cite journal \| author=Taviaux S \|title=Assignment of thyroid hormone responsive SPOT 14 homolog (THRSP) to human chromosome 11 bands q13.5→q14.1 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=76 \|issue= 3–4 \|pages= 219–20 \|year= 1997 \|pmid= 9186528 \|doi=10.1159/000134553 \|name-list-format=vanc\| author2=Planells R \| author3=Gastaldi M \| display-authors=3 \| last4=Torresani \| first4=J. \| last5=Grillasca \| first5=J.P. }}
	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
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	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}
	*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R }}		*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R \|s2cid=4427026 }}
	*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-format=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}		*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-format=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}
	{{refend}}		{{refend}}

← Previous revision		Revision as of 09:09, 30 May 2020
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	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD \| bibcode=2002PNAS...9916899M }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}

← Previous revision		Revision as of 18:49, 12 May 2020
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	This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />		This gene has been shown to be expressed in liver and [[adipocyte]]s, particularly in [[lipoma]]tous modules. It is also found to be expressed in lipogenic [[breast cancer]]s, which suggests a role in controlling tumor [[lipid metabolism]].<ref name="entrez" />

	Previously, THRSP was among the identified upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|last=dela Peña\|first=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior~~\|url=https://linkinghub.elsevier.com/retrieve/pii/S0166432815003411~~\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|last=Custodio\|first=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice~~\|url=https://linkinghub.elsevier.com/retrieve/pii/S0306452218305463~~\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008}}</ref>		Previously, THRSP was among the identified upregulated genes in the prefrontal cortex of spontaneously hypertensive rats (SHR/NCrl) and Wistar-Kyoto (WKY/NCrl) rats which exhibited inattention behavior.<ref>{{Cite journal\|last=dela Peña\|first=Ike\|last2=Bang\|first2=Minji\|last3=Lee\|first3=Jinhee\|last4=de la Peña\|first4=June Bryan\|last5=Kim\|first5=Bung-Nyun\|last6=Han\|first6=Doug Hyun\|last7=Noh\|first7=Minsoo\|last8=Shin\|first8=Chan Young\|last9=Cheong\|first9=Jae Hoon\|date=September 2015\|title=Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior\|journal=Behavioural Brain Research\|language=en\|volume=291\|pages=268–276\|doi=10.1016/j.bbr.2015.05.012\|pmid=26048425}}</ref> Subsequently, overexpression of THRSP induced inattention, but not hyperactive and impulsive behavior in mice, suggesting that this gene plays a role in the inattention phenotype of ADHD.<ref>{{Cite journal\|last=Custodio\|first=Raly James Perez\|last2=Botanas\|first2=Chrislean Jun\|last3=de la Peña\|first3=June Bryan\|last4=dela Peña\|first4=Irene Joy\|last5=Kim\|first5=Mikyung\|last6=Sayson\|first6=Leandro Val\|last7=Abiero\|first7=Arvie\|last8=Ryoo\|first8=Zae Young\|last9=Kim\|first9=Bung-Nyun\|last10=Kim\|first10=Hee Jin\|last11=Cheong\|first11=Jae Hoon\|date=October 2018\|title=Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in Mice\|journal=Neuroscience\|language=en\|volume=390\|pages=141–150\|doi=10.1016/j.neuroscience.2018.08.008\|pmid=30138648}}</ref>

	==References==		==References==
Line 18:		Line 18:
	*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}		*{{cite journal \| author=Moncur JT \|title=Assignment of the "spot 14" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization \|journal=Cytogenet. Cell Genet. \|volume=78 \|issue= 2 \|pages= 131–2 \|year= 1997 \|pmid= 9371405 \|doi=10.1159/000134644 \|name-list-format=vanc\| author2=Park JP \| author3=Maloney M \| display-authors=3 \| last4=Mohandas \| first4=T.K. \| last5=Kinlaw \| first5=W.B. }}
	*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}		*{{cite journal \|vauthors=Cunningham BA, Maloney M, Kinlaw WB \|title=Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo \|journal=Endocrinology \|volume=138 \|issue= 12 \|pages= 5184–8 \|year= 1997 \|pmid= 9389499 \|doi=10.1210/en.138.12.5184 \|doi-access=free }}
	*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB }}		*{{cite journal \| author=Moncur JT \|title=The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=95 \|issue= 12 \|pages= 6989–94 \|year= 1998 \|pmid= 9618526 \|doi=10.1073/pnas.95.12.6989 \| pmc=22712 \|name-list-format=vanc\| author2=Park JP \| author3=Memoli VA \| display-authors=3 \| last4=Mohandas \| first4=TK \| last5=Kinlaw \| first5=WB \|bibcode=1998PNAS...95.6989M }}
	*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD }}		*{{cite journal \| author=Strausberg RL \|title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences \|journal=Proc. Natl. Acad. Sci. U.S.A. \|volume=99 \|issue= 26 \|pages= 16899–903 \|year= 2003 \|pmid= 12477932 \|doi= 10.1073/pnas.242603899 \| pmc=139241 \|name-list-format=vanc\| author2=Feingold EA \| author3=Grouse LH \| display-authors=3 \| last4=Derge \| first4=JG \| last5=Klausner \| first5=RD \| last6=Collins \| first6=FS \| last7=Wagner \| first7=L \| last8=Shenmen \| first8=CM \| last9=Schuler \| first9=GD }}
	*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}		*{{cite journal \|vauthors=Campbell MC, Anderson GW, Mariash CN \|title=Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification \|journal=Endocrinology \|volume=144 \|issue= 12 \|pages= 5242–8 \|year= 2004 \|pmid= 12960053 \|doi= 10.1210/en.2002-0008 \|doi-access= free }}
	*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}		*{{cite journal \| author=Gerhard DS \|title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) \|journal=Genome Res. \|volume=14 \|issue= 10B \|pages= 2121–7 \|year= 2004 \|pmid= 15489334 \|doi= 10.1101/gr.2596504 \| pmc=528928 \|name-list-format=vanc\| author2=Wagner L \| author3=Feingold EA \| display-authors=3 \| last4=Shenmen \| first4=CM \| last5=Grouse \| first5=LH \| last6=Schuler \| first6=G \| last7=Klein \| first7=SL \| last8=Old \| first8=S \| last9=Rasooly \| first9=R }}
	*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija }}		*{{cite journal \| author=Rual JF \|title=Towards a proteome-scale map of the human protein-protein interaction network \|journal=Nature \|volume=437 \|issue= 7062 \|pages= 1173–8 \|year= 2005 \|pmid= 16189514 \|doi= 10.1038/nature04209 \|name-list-format=vanc\| author2=Venkatesan K \| author3=Hao T \| display-authors=3 \| last4=Hirozane-Kishikawa \| first4=Tomoko \| last5=Dricot \| first5=Amélie \| last6=Li \| first6=Ning \| last7=Berriz \| first7=Gabriel F. \| last8=Gibbons \| first8=Francis D. \| last9=Dreze \| first9=Matija \|bibcode=2005Natur.437.1173R }}
	*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-format=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}		*{{cite journal \| author=Chou WY \|title=Human spot 14 protein interacts physically and functionally with the thyroid receptor \|journal=Biochem. Biophys. Res. Commun. \|volume=357 \|issue= 1 \|pages= 133–8 \|year= 2007 \|pmid= 17418816 \|doi= 10.1016/j.bbrc.2007.03.103 \|name-list-format=vanc\| author2=Cheng YS \| author3=Ho CL \| display-authors=3 \| last4=Liu \| first4=Shu-Ting \| last5=Liu \| first5=Pei-Yao \| last6=Kuo \| first6=Chen-Chin \| last7=Chang \| first7=Hui-Ping \| last8=Chen \| first8=Yu-Hou \| last9=Chang \| first9=Gu-Gang }}
	{{refend}}		{{refend}}