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Orotic aciduria: Revision history


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  • curprev 10:1510:15, 13 October 2021 Sramonmaiques talk contribs 6,384 bytes +6 Since the discovery of orotic aciduria, two other diseases have been related to defects in enzymes of the de novo pyrimidine synthesis pathway: in 2010, Miller syndrome was shown to be caused by mutation in dihydroorotate dehydrogenase; in 2015, the first case of a young children with CAD-deficiency was described. undo

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