Myocarditis: Difference between revisions

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Add reference to more resent study on Myocardial Injury
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Undid revision 1225175918 by Dxaudit (talk) Significance of this is unclear as participants who had elevated troponin after mRNA Covid vaccine did not have cardiac MRI, ultrasound or biopsy to confirm myocarditis. This is only a biochemical marker of cardiac injury. And the authors noted: all cases of biomarker elevation were mild, transient, none had ECG changes/major cardiac events. All cases were Subclinical
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==== Vaccination ====
* Myocarditis and [[pericarditis]] can be a rare side effect of some vaccines like the [[Smallpox vaccination|smallpox vaccine]].<ref name="pmid29572367">{{cite journal | vauthors = Keinath K, Church T, Kurth B, Hulten E | title = Myocarditis secondary to smallpox vaccination | journal = BMJ Case Reports | volume = 2018 | issue = | pages = | date = March 2018 | pmid = 29572367 | pmc = 5878341 | doi = 10.1136/bcr-2017-223523 }}</ref>
* Myocarditis can be a rare side-effect of the Covid-19 [[mRNA vaccine]]s. The [[FDA]] and [[European Medicines Agency]] estimates the risk of myocarditis after the Covid-19 vaccine as 1 case per 100,000 of those who are vaccinated.<ref name="Basso NEJM" /><ref>{{cite journal |vauthors=Ling RR, Ramanathan K, Tan FL, Tai BC, Somani J, Fisher D, MacLaren G |title=Myopericarditis following COVID-19 vaccination and non-COVID-19 vaccination: a systematic review and meta-analysis |journal=Lancet Respir Med |volume=10 |issue=7 |pages=679–688 |date=July 2022 |pmid=35421376 |pmc=9000914 |doi=10.1016/S2213-2600(22)00059-5 |type=Systematic review}}</ref> The risk of myocarditis after Covid-19 vaccination was observed to be highest in males between 16–29 years of age, and after receiving the second dose of the mRNA Covid-19 vaccine.<ref name="biontech">{{cite journal | vauthors = Oster ME, Shay DK, Su JR, Gee J, Creech CB, Broder KR, Edwards K, Soslow JH, Dendy JM, Schlaudecker E, Lang SM, Barnett ED, Ruberg FL, Smith MJ, Campbell MJ, Lopes RD, Sperling LS, Baumblatt JA, Thompson DL, Marquez PL, Strid P, Woo J, Pugsley R, Reagan-Steiner S, DeStefano F, Shimabukuro TT | display-authors = 6 | title = Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021 | journal = JAMA | volume = 327 | issue = 4 | pages = 331–340 | date = January 2022 | pmid = 35076665 | pmc = 8790664 | doi = 10.1001/jama.2021.24110 }}</ref><ref name="NEJM Mevoarach">{{cite journal |vauthors=Mevorach D, Anis E, Cedar N, Bromberg M, Haas EJ, Nadir E, Olsha-Castell S, Arad D, Hasin T, Levi N, Asleh R, Amir O, Meir K, Cohen D, Dichtiar R, Novick D, Hershkovitz Y, Dagan R, Leitersdorf I, Ben-Ami R, Miskin I, Saliba W, Muhsen K, Levi Y, Green MS, Keinan-Boker L, Alroy-Preis S |display-authors=6 |title=Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel |journal=New England Journal of Medicine |date=2 December 2021 |volume=385 |issue=23 |pages=2140–2149 |doi=10.1056/NEJMoa2109730|pmid=34614328 |pmc=8531987 }}</ref> For this high-risk group, incidence of myocarditis has been reported to be more than 1 case per 10,000.<ref>{{Cite web |last=tproveau |date=2022-10-14 |title=Do Vaccines Cause Myocarditis and/or Myocardopathy? |url=https://www.vaccinesafety.edu/do-vaccines-cause-myocarditis-and-or-myocardopathy/ |access-date=2023-01-08 |website=Institute for Vaccine Safety |language=en-US}}</ref>However a study on Sex-specific differences in mycardial injury released 2023 indicates a risk of roughly 1 in 35 (22 from sample size of 764).<ref name="ejhf2978">{{cite journal | vauthors =Natacha B, Pedro L, Julia H, Philip M, Daniela M, Noemi G | title = Sex-specific differences in myocardial injury incidence after COVID-19 mRNA-1273 booster vaccination | journal = European Journal of Hearth Failure | volume = 25 | issue =10 | pages = 1871–1881 | date = October 2023 | doi = 10.1002/ejhf.2978 }}</ref>
 
=== Physical injuries ===