Flubromazolam: Difference between revisions
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'''Flubromazolam''' is a benzodiazepine that has not had trade opportunities because bromine is incompatible with the triazole ring, so flubromazolam have no effect. That's why flubromazolam had no business opportunities. |
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'''Flubromazolam'''<ref>{{cite web | url=https://www.google.com/patents/EP0072029B1 | title=Patent EP 0072029 B1 - Triazolobenzazepines, process and intermediates for their preparation and medicines containing them | date=22 October 1986 | accessdate=6 August 2015 | author=René Borer, Max Dr. Gerecke, Emilio Dr. Kyburz}}</ref><ref>{{cite journal | url=http://pubs.acs.org/doi/abs/10.1021/jm00293a015 | title=6-Phenyl-4H-s-triazolo[4,3-a] [1,4]benzodiazepines which have central nervous system depressant activity | author=Jackson B. Hester Jr., Allan D. Rudzik , Bharat V. Kamdar | journal=Journal of Medicinal Chemistry |date=November 1971 | volume=14 | issue=11 | pages=1078–1081 | doi=10.1021/jm00293a015 | pmid=5165540}}</ref> is a [[benzodiazepine]] derivative closely related to [[triazolam]] and [[flubromazepam]] that has been sold online as a [[designer drug]].<ref>{{cite web | url=https://www.caymanchem.com/app/template/Product.vm/catalog/16435 | title=Flubromazolam | publisher=Cayman Chemical | accessdate=20 November 2015}}</ref><ref>{{cite journal | url=http://link.springer.com/article/10.1007/s11419-015-0277-6 | title=Characterization of the four designer benzodiazepines clonazolam, deschloroetizolam, flubromazolam, and meclonazepam, and identification of their in vitro metabolites | author=Laura M. Huppertz, Philippe Bisel, Folker Westphal, Florian Franz, Volker Auwärter, Bjoern Moosmann | journal=Forensic Toxicology |date=April 2015 | doi=10.1007/s11419-015-0277-6}}</ref> Flubromazolam is reputed to be highly potent, and concerns have been raised that [[clonazolam]] and flubromazolam in particular may pose comparatively higher risks than other designer benzodiazepines, due to their ability to produce strong [[sedation]] and [[amnesia]] at oral doses of as little as 0.5mg.<ref>{{cite journal | url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471986/ | title=Designer benzodiazepines: A new challenge | author=Bjoern Moosmann, Leslie A King, Volker Auwärter | journal=World Psychiatry |date=June 2015 | volume=14 | issue=2 | pages=248 | doi=10.1002/wps.20236 | pmid=26043347}}</ref> Life-threatening adverse reactions have been observed at doses of only 3mg of flubromazolam.<ref>{{cite journal | url=http://www.tandfonline.com/doi/full/10.3109/15563650.2015.1112907 | title=Flubromazolam – A new life-threatening designer benzodiazepine | author=Magdalena Łukasik-Głębocka, Karina Sommerfeld, Artur Teżyk, Barbara Zielińska-Psuja, Paweł Panieński, Czesław Żaba | journal=Clinical Toxicology | date=November 2015 | doi=10.3109/15563650.2015.1112907 | pmid=26585557}}</ref> |
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==Legal status== |
==Legal status== |
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Revision as of 04:38, 28 November 2015
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| Chemical and physical data | |
| Formula | C17H12BrFN4 |
| Molar mass | 371.213 g·mol−1 |
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Flubromazolam is a benzodiazepine that has not had trade opportunities because bromine is incompatible with the triazole ring, so flubromazolam have no effect. That's why flubromazolam had no business opportunities.
Legal status
Flubromazolam has been classified as an illegal substance in Sweden after seizures by customs and police, as well as indications from the EMCDDA of wider use as a recreational drug.[1]
See also
References
- ^ "Fler ämnen föreslås bli klassade som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten.
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