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Sidney M. Wolfe

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For the American astrophysicist, see Sidney C. Wolff.
Sidney M. Wolfe
Born
Sidney Manuel Wolfe

(1937-06-12)June 12, 1937
Cleveland, Ohio, U.S.
DiedJanuary 1, 2024(2024-01-01) (aged 86)
Washington, D.C., U.S.
Alma materCase Western University
OccupationPhysician
Known forHealth Research Group
AwardsMacArthur Fellows Program

Sidney Manuel Wolfe (June 12, 1937 – January 1, 2024) was an American physician and the co-founder and director of Public Citizen's Health Research Group, a consumer and health advocacy lobbying organization.[1] He publicly crusaded against many pharmaceutical drugs, which he believed to be a danger to public health.

Early life and education

Wolfe was born in Cleveland on June 12, 1937. His father was a workplace safety inspector for the Labor Department and his mother was an English teacher.[2]

In 1959, he received a BA in chemical engineering from Cornell University. While working at a summer job, he received first degree burns from hydrofluoric acid that made him decide not to pursue chemistry as a career. In 1965, he received a medical degree from Western Reserve University (now Case Western Reserve University). He trained under pediatrician Benjamin Spock.[2]

Career

After earning his medical degree at Case Western Reserve University, Cleveland, Ohio, Wolfe completed an internship and residency in internal medicine.[citation needed] Beginning in 1966 he researched blood-clotting and alcoholism at the National Institutes of Health.[3] He met consumer advocate Ralph Nader in Washington, D.C. at a meeting of the American Patients Association, and advised Nader on health problems in the United States.[citation needed] Wolfe co-founded the consumer lobbying organization Health Research Group with Nader in 1971. He and Nader wrote a letter to the F.D.A. about contaminated intravenous fluid bags made by Abbott Laboratories which they then released to the news media. Two million bags were recalled two days later.[4][5]

For more than 30 years, Wolfe campaigned to have propoxyphene (Darvon, Darvocet) removed from the American market, because it can cause heart arrhythmias. In 2009, a U.S. Food and Drug Administration (FDA) advisory panel recommended that it be withdrawn from the market.[6] The recommendation to ban the drug was ultimately not upheld and instead manufacturers were required to place additional warning labels on packaging. In 2009, Wolfe was appointed to the FDA's Drug Safety and Risk Management Committee.[7] On November 19, 2010, the FDA recommended against continued prescribing and use of propoxyphene.[8]

Other drugs that Wolfe has campaigned against include Yaz, Yasmin,[9] Phenacetin, Oraflex, Zomax, Vioxx,[10] and Crestor.[11]

In 1995, he became an Adjunct Professor of Internal Medicine at the Case Western Reserve University School of Medicine.[3]

Wolfe was interviewed on television by Phil Donahue, Barbara Walters, Bill Moyers,[12] and Oprah Winfrey, and wrote for the Huffington Post.[13]

Wolfe was a member of the Society of General Internal Medicine.[citation needed]

Wolfe retired from his position as director of the Health Research Group in 2013,[3] He continued in the role of senior adviser.[14]

Awards

Personal life

Wolfe was first married to Ava Albert. Together they had four children. The marriage ended in divorce. In 1978, he married Suzanne Goldberg, a clinical psychologist and artist.[2]

Wolfe died of a brain tumor on January 1, 2024, at the age of 86.[2]

Works

Books

  • Off Diabetes Pills: A Diabetic's Guide to Longer Life (1978) with Rebecca Warner; Health Research Group ISBN 9789996451034
  • Pills That Don't Work: A Consumers' and Doctors' Guide to Over 600 Prescription Drugs That Lack Evidence of Effectiveness; Farrar, Straus & Giroux; Revised edition (1981), with Christopher M. Coley & the Health Research Group OL 4259817M, ISBN 9780374233419
  • Worst Pills, Best Pills: A Consumer's Guide to Avoiding Drug-Induced Death or Illness (1990), with Larry D. Sasich and Peter Lurie; Gallery Books
  • Torrey, E. Fuller; Stieber, Joan; Ezekiel, Jonathan; Wolfe, Sidney M; Sharfstein, Joshua; Noble, John H; Flynn, Laurie M (1992), Criminalizing the Seriously Mentally Ill: The Abuse of Jails as Mental Hospitals, A joint report of the National Alliance for the Mentally Ill and Public Citizen's Health Research Group, ISBN 0-7881-4279-8, retrieved 12 November 2010
  • Unnecessary Cesarean Sections: Curing a National Epidemic State Report for Illinois, with Mary Gabay & the Public Citizen Group (1994) OL 11507865M, ISBN 9780937188552
  • Questionable Doctors; Disciplined by States or the Federal Government; Public Citizen Health Research Group; 1996 edition ISBN 9780937188057
    • 2,815 Questionable Doctors; Disciplined by State and Federal Governments, Region 4: California, Hawaii, with Phyllis McCarthy, John Paul Fawcett, and Benita Marcus Adler; Public Citizen's Health Research Group; 2002 editionASIN B0014099QQ

Articles, book chapters

References

  1. ^ "Health and Safety Recent Work". citizen.org. Retrieved 30 January 2015.
  2. ^ a b c d Rosenwald, Michael (January 1, 2024). "Sidney Wolfe, relentless consumer activist and FDA foe, dies at 86". Washington Post.
  3. ^ a b c "Sidney Wolfe, MD". Public Citizen.
  4. ^ Risen, Clay (January 3, 2024). "Sidney M. Wolfe, Scourge of the Pharmaceutical Industry, Dies at 86". New York Times.
  5. ^ Okie, Susan (December 5, 1989). "Running on Outrage". Washington Post.
  6. ^ "FDA Advisers: Ban Painkiller Darvon". CBS news. January 30, 2009.
  7. ^ Goldstein, Jacob (January 9, 2009). "Sidney Wolfe: Outsider Becomes FDA Insider". Wall Street Journal.
  8. ^ "FDA Drug Safety Communication: FDA recommends against the continued use of propoxyphene". fda.gov. Retrieved 30 January 2015.
  9. ^ "The Yaz Men: Members of FDA panel reviewing the risks of popular Bayer contraceptive had industry ties". Washington Monthly. January 9, 2012.
  10. ^ Harris, Gardiner (February 15, 2005). "Drug Industry's Longtime Critic Says 'I Told You So'". New York Times.
  11. ^ "Testimony of Sidney M. Wolfe, M.D. before the FDA Endocrinologic and Metabolic Drugs Advisory Committee Hearing on Rosuvastatin | HRG Publication #1669". Health Research Group. July 9, 2003.
  12. ^ Bill Moyers (May 22, 2009). "Dr. David Himmelstein & Dr. Sidney Wolfe". PBS.
  13. ^ "FDA: Cautious on food safety - reckless on prescription drug safety". Huffington Post. May 15, 2010.
  14. ^ "Stepping Aside but Not Out: Well-Known Consumer Health Advocate Dr. Sidney Wolfe Hands over Reins to Deputy". Public Citizen. 3 June 2013.
  15. ^ "Sidney M. Wolfe | Physician and Public Health Leader". MacArthur Foundation.
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