Apigenin

Apigenin^[1]
Names
	IUPAC name 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Identifiers
CAS Number	520-36-5;
3D model (JSmol)	Interactive image;
ECHA InfoCard	100.007.540
CompTox Dashboard (EPA)	DTXSID6022391 ;
	SMILES OC1=C(C(C=C(C3=CC=C(O); C=C3)O2)=O)C2=CC(O)=C1;
Properties
Chemical formula	C15H10O5
Molar mass	270.23 g/mol
Melting point	345-350 °C
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Apigenin is a flavone that is the aglycone of apiin, isolated from parsley and celery, and apigetrin. It is a yellow crystalline solid that has been used to dye wool.

Apigenin is a potent inhibitor of CYP2C9,^[2] an enzyme responsible for the metabolism of many pharmaceutical drugs in the body.

References

^ Merck Index, 11th Edition, 763.
^ Si Dayong, Wang Y, Zhou Y-H, Guo Y, Wang J, Zhou H, Li Z-S, Fawcett JP (2009). "Mechanism of CYP2C9 inhibition by flavones and flavonols" (PDF). Drug Metabolism and Disposition. 37: 629-634. doi:10.1124/dmd.108.023416. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

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[1] Merck Index, 11th Edition, 763.

[Si_2009-2] Si Dayong, Wang Y, Zhou Y-H, Guo Y, Wang J, Zhou H, Li Z-S, Fawcett JP (2009). "Mechanism of CYP2C9 inhibition by flavones and flavonols" (PDF). Drug Metabolism and Disposition. 37: 629-634. doi:10.1124/dmd.108.023416. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

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