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Naftidrofuryl

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Naftidrofuryl
Clinical data
Routes of
administration
Oral
ATC code
Identifiers
  • 2-(diethylamino)ethyl 3-(1-naphthyl)-2-(tetrahydrofuran-2-ylmethyl)propanoate
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.045.960 Edit this at Wikidata
Chemical and physical data
FormulaC24H33NO3
Molar mass383.524 g/mol g·mol−1

Naftidrofuryl (INN, also known as nafronyl or as the oxalate salt nafronyl oxalate) is a drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic.[1] It may also be a 5-HT2 receptor antagonist.

It is sold under the brand name Dusodril (Merck).

Historically, it has been used to treat sudden idiopathic hearing loss and acute tinnitus.[2]

References

  1. ^ Reynolds, J.E.F. (ed.) (1993). Martindale: The extra pharmacopoeia (30th edition ed.). London: Pharmaceutical Press. p. 1310. ISBN 0853693005. {{cite book}}: |author= has generic name (help); |edition= has extra text (help)
  2. ^ http://www.der-arzneimittelbrief.de/Jahrgang2004/Ausgabe12Seite89.htm