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Bucumolol
Names
IUPAC name
8-[3-(tert -Butylamino)-2-hydroxypropoxy]-5-methylchromen-2-one
Identifiers
ChEMBL
ChemSpider
KEGG
MeSH
C024221
UNII
InChI=1S/C17H23NO4/c1-11-5-7-14(16-13(11)6-8-15(20)22-16)21-10-12(19)9-18-17(2,3)4/h5-8,12,18-19H,9-10H2,1-4H3
Key: CIJVBYRUFLGDHY-UHFFFAOYSA-N
InChI=1/C17H23NO4/c1-11-5-7-14(16-13(11)6-8-15(20)22-16)21-10-12(19)9-18-17(2,3)4/h5-8,12,18-19H,9-10H2,1-4H3
Key: CIJVBYRUFLGDHY-UHFFFAOYAD
CC1=C2C=CC(=O)OC2=C(C=C1)OCC(CNC(C)(C)C)O
Properties
C 17 H 23 N O 4
Molar mass
305.374 g·mol−1
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
Bucumolol is a beta-adrenergic antagonist .[ 1]
References
^ Nakayama, K; Oshima, T; Koike, H (1981). "Assessment of beta-blockade and the non-specific effect of bucumolol, a beta-adrenergic blocking agent, on atrioventricular conduction in anesthetized dogs". Archives Internationales de Pharmacodynamie et de Thérapie . 254 (1): 145–56. PMID 6121536 .
α1
Agonists Antagonists
Abanoquil
Ajmalicine
Alfuzosin
Anisodamine
Anisodine
Atiprosin
Atypical antipsychotics (e.g., brexpiprazole , clozapine , olanzapine , quetiapine , risperidone )
Benoxathian
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Buflomedil
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Corynanthine
Dapiprazole
Domesticine
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Etoperidone
Fenspiride
Hydroxyzine
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L-765,314
mCPP
Mepiprazole
Metazosin
Monatepil
Moxisylyte
Naftopidil
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Neldazosin
Niaprazine
Niguldipine
Pardoprunox
Pelanserin
Perlapine
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Piperoxan
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Tricyclic antidepressants (e.g., amitriptyline , clomipramine , doxepin , imipramine , trimipramine )
Trimazosin
Typical antipsychotics (e.g., chlorpromazine , fluphenazine , loxapine , thioridazine )
Urapidil
WB-4101
Zolertine
α2
Agonists Antagonists
1-PP
Adimolol
Amesergide
Aptazapine
Atipamezole
Atypical antipsychotics (e.g., asenapine , brexpiprazole , clozapine , lurasidone , olanzapine , paliperidone , quetiapine , risperidone , zotepine )
Azapirones (e.g., buspirone , gepirone , ipsapirone , tandospirone )
BRL-44408
Buflomedil
Cirazoline
Efaroxan
Esmirtazapine
Fenmetozole
Fluparoxan
Idazoxan
Ketanserin
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mCPP
Mianserin
Mirtazapine
NAN-190
Pardoprunox
Phentolamine
Phenoxybenzamine
Piperoxan
Piribedil
Rauwolscine
Rotigotine
Setiptiline
Spegatrine
Spiroxatrine
Sunepitron
Terguride
Tolazoline
Typical antipsychotics (e.g., chlorpromazine , fluphenazine , loxapine , thioridazine )
Yohimbine
β