Lipolysis

Molecula triacyloglyceroli (TAG, "pingue") in adipocyto (cellula adipata) invenitur. Lipolyse TAG gradatim in acida adipata tria sua secatum est. Productum terminale est glycerolum.

Lipolysis est iter metabolicum, quo cellulae corporis pingui materiam pinguem tollitur.

Intra cellulam, adipocytum^[1], pingue moleculae triacyloglyceroli (TAG). Lipolysis enzymorum lipolyticorum ope gradatim moleculas TAG secat:

Triacyloglycerolum (TAG) → Diacyloglycerolum (DAG)
Diacyloglycerolum (DAG) → Monoacyloglycerolum (MAG)
Monoacyloglycerolum (MAG) → Glycerolum

Ope hormontum et quorundam medicamentorum et aliarum substantiarum lipolysis et augeri et inhiberi queat. In senectute lipolysis diminuta est^[2], quod incrementum ponderis pinguis haud minore in parte explicat.

Adipositas, diaeta et lipolysis

Non potest, ut corporis pingue incendatur et comburatur; tantum pinguem, quod energia conservata est, in usu ponere licet. Ad ponderis perdendum multitudo insulinum in sanguine maiore in parte multitudinem lipolysis inverse iubet: Praesentia insulini inhibeat lipolysem (modum conservandi), absentia insulini augeat lipolysem (modum liberandi)^[3]. Imprimis sub nutrimentum hodiernum multitudo insulini ad valores altiores (hyperinsulinaemiam) inclinat. Imprimis "intercenae" signum endocrineum rediens ponant, valores insulini augens. Gubernatio pinguis, de aequilibrio insulini, non de multitudinibus carbohydratum pendit.

Pinacotheca

Notae

↑ Yang A., Mottillo E. P. (Mar 2020). "Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics". The biochemical journal 477 (5): 985-1008
↑ Gao H., Arner P., Beauchef G., Guéré C., Vie K., Dahlman I., Mejhert N., Rydén M. (Iul 2020). "Age-Induced Reduction in Human Lipolysis: A Potential Role for Adipocyte Noradrenaline Degradation". Cell metabolism 32 (1): 1-3
↑ Choi S. M., Tucker D. F., Gross D. N., Easton R. M., DiPilato L. M., Dean A. S., Monks B. R., Birnbaum M. J. (Nov 2010). "Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway". Molecular and cellular biology 30 (21): 5009-20 doi:10.1128/MCB.00797-10

Nexus interni

Nexus externi

cambridge.org: Gubernatio lipolysis enzymaticae (Anglice)

[1] Yang A., Mottillo E. P. (Mar 2020). "Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics". The biochemical journal 477 (5): 985-1008

[2] Gao H., Arner P., Beauchef G., Guéré C., Vie K., Dahlman I., Mejhert N., Rydén M. (Iul 2020). "Age-Induced Reduction in Human Lipolysis: A Potential Role for Adipocyte Noradrenaline Degradation". Cell metabolism 32 (1): 1-3

[3] Choi S. M., Tucker D. F., Gross D. N., Easton R. M., DiPilato L. M., Dean A. S., Monks B. R., Birnbaum M. J. (Nov 2010). "Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway". Molecular and cellular biology 30 (21): 5009-20 doi:10.1128/MCB.00797-10

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