CEACAM8
| CEACAM8 | |
| Нинди таксонда бар | H. sapiens[d][1] |
|---|---|
| Кодлаучы ген | CEACAM8[d][1] |
| Молекуляр функция | связывание с белками плазмы[d][2] һәм protein heterodimerization activity[d][3] |
| Күзәнәк компоненты | anchored component of membrane[d][4], күзәнәк мембранасы[d][4][5][4], күзәнәк мембранасы өлеше[d][6], экзосома[d][7], мембрана[d][4], күзәнәк тышындагы мохит[d][5][8], azurophil granule membrane[d][4], specific granule membrane[d][4], tertiary granule membrane[d][4], күзәнәк өслеге[d][4][9] һәм экзосома[d][10] |
| Биологик процесс | иммун җавап[d][11], leukocyte migration[d][4], neutrophil degranulation[d][4], агрегация клеток[d][4] һәм heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules[d][12][9] |
CEACAM8 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[13][14]
Искәрмәләр
- ↑ 1,0 1,1 UniProt
- ↑ Singer B. B., Scheffrahn I., Heymann R. et al. Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes // J. Immunol. — Baltimore: 2002. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.168.10.5139 — PMID:11994468
- ↑ Günther S., Sundberg E. J. Diverse oligomeric states of CEACAM IgV domains // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — [Washington, etc.], USA: National Academy of Sciences [etc.], 2015. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.1509511112 — PMID:26483485
- ↑ 4,00 4,01 4,02 4,03 4,04 4,05 4,06 4,07 4,08 4,09 4,10 GOA
- ↑ 5,0 5,1 F. Arakawa, M. Kuroki, Y. Misumi et al. Characterization of a cDNA clone encoding a new species of the nonspecific cross-reacting antigen (NCA), a member of the CEA gene family // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier BV, 1990. — ISSN 0006-291X; 1090-2104 — doi:10.1016/0006-291X(90)90975-S — PMID:2306228
- ↑ B Berling, F Kolbinger, F Grunert et al. Cloning of a carcinoembryonic antigen gene family member expressed in leukocytes of chronic myeloid leukemia patients and bone marrow // Cancer Res. / G. C. Prendergast — American Association for Cancer Research, 1990. — ISSN 0008-5472; 1538-7445 — PMID:2208113
- ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
- ↑ Thaysen-Andersen M., Loke I., Packer N. Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2015. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M114.631622 — PMID:25645918
- ↑ 9,0 9,1 Yamanaka T, Kuroki M, Kinugasa T et al. Preparation and characterization of two human carcinoembryonic antigen family proteins of neutrophils, CD66b and c, in silkworm larvae // PREP — Elsevier BV, 1996. — ISSN 1046-5928; 1096-0279 — doi:10.1006/PREP.1996.0065 — PMID:8776764
- ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
- ↑ B Berling, F Kolbinger, F Grunert et al. Cloning of a carcinoembryonic antigen gene family member expressed in leukocytes of chronic myeloid leukemia patients and bone marrow // Cancer Res. / G. C. Prendergast — American Association for Cancer Research, 1990. — ISSN 0008-5472; 1538-7445 — PMID:2208113
- ↑ Kuroki M, Abe H, Imakiirei T et al. Identification and comparison of residues critical for cell-adhesion activities of two neutrophil CD66 antigens, CEACAM6 and CEACAM8 // J. Leukoc. Biol. / L. Montaner — Wiley-Blackwell, 2001. — ISSN 0741-5400; 1938-3673 — PMID:11590190
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
Чыганаклар
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)
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Бу — аксым турында мәкалә төпчеге. Сез мәкаләне үзгәртеп һәм мәгълүмат өстәп,  Википедия проектына ярдәм итә аласыз.
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