UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase

In enzymology, an UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase (EC 2.6.1.34) is an enzyme that catalyzes the chemical reaction

UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose + 2-oxoglutarate $\rightleftharpoons$ UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-glutamate

Thus, the two substrates of this enzyme are UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose and 2-oxoglutarate, whereas its two products are UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase. Other names in common use include uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose, and aminotransferase. It employs one cofactor, pyridoxal phosphate.

References

• Distler J, Kaufman B, Roseman S (1966). "Enzymic synthesis of a diamino sugar nucleotide by extracts of type XIV Diplococcus pneumoniae". Arch. Biochem. Biophys. 116: 466–78. doi:10.1016/0003-9861(66)90054-3. PMID 4381351.{{cite journal}}: CS1 maint: multiple names: authors list (link)

External links

The CAS registry number for this enzyme class is Template:CAS registry.