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Aspartic acid

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Aspartic acid
Systematic name (S)-Aminobutanedioic acid
Abbreviations Asp
D
Chemical formula C4H7NO4
Molecular mass 133.10 g/mol
Melting point 270-271 °C
Density 1.66 g cm-3
Isoelectric point 2.77
pKa 1.95
3.71
9.66
CAS number [56-84-8]
EINECS number 200-291-6
SMILES OC(=O)CC(N)C(=O)O
Chemical structure of Aspartic acid
Disclaimer and references

Aspartic acid, also known as aspartate, the name of its anion, is one of the 20 natural proteinogenic amino acids which are the building blocks of proteins.

Its three-letter abbreviation is Asp, and its one-letter abbreviation is D. A three-letter designation for either asparagine or aspartic acid is Asx (one-letter abbreviation: B).

As its name indicates, it is the carboxylic acid analog of asparagine. It is non-essential in mammals, and might serve as an excitatory neurotransmitter in the brain. It is also a metabolite in the urea cycle, and participates in gluconeogenesis.

This neurotransmitter may provide resistance to fatigue and thus lead to possessing more endurance, although the evidence to support this idea is not strong.

See also