Catecholamine

Catecholamines are chemical compounds derived from the amino acid tyrosine that act as hormones or neurotransmitters.

The most abundant catecholamines are epinephrine (adrenaline), norepinephrine (noradrenaline) and dopamine. They are produced mainly from the adrenal medulla and the postganglionic fibers of the sympathetic nervous system. Adrenaline acts as a neurotransmitter in the central nervous system and as a hormone in the blood circulation. Noradrenaline is primarily a neurotransmitter of the peripheral sympathetic nervous system but is also present in the blood (mostly through "spillover" from the synapses of the sympathetic system).

Catecholamines levels in blood are associated with stress. Catecholamines cause general physiological changes that prepare the body for physical activity (e.g. exercise). Some typical effects are increases in heart rate, blood pressure, and blood glucose levels. Some drugs, like selegiline, raise the levels of all the catecholamines.