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Nitrogen mustard

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The nitrogen mustards are cytotoxic chemotherapy agents similar to mustard gas. The prototype nitrogen mustard drug is mustine which is no longer commonly in use but was the first drug to be used as an anticancer chemotherapeutic. It is a schedule 1 substance in the Chemical Weapons Convention.

Other nitrogen mustards include cyclophosphamide, chlorambucil, uramustine and melphalan.

Some nitrogen mustards are usable as blistering agents (chemical weapons). These are eg.:

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