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Src (gene)

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This is an old revision of this page, as edited by Brim (talk | contribs) at 09:07, 3 December 2005 (+cat oncogenes). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

src: The transforming (sarcoma inducing) gene of Rous sarcoma virus. The protein product is pp60vsrc, a cytoplasmic protein with tyrosine-specific protein kinase activity, that associates with the cytoplasmic face of the plasma membrane.

Src tyrosine kinases transmit integrin-dependent signals central to cell movement and proliferation.