Chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is an umbrella term for a group of respiratory tract diseases that are characterised by airflow limitation.
COPD is also known as CORD, COAD, COLD, and many other acronyms, these three are short for chronic obstructive respiratory, airways, or lung disease. CAL refers to the same disease, and stands for chronic airway limitation.
Conditions grouped here are:
COPD is characterised by an increased residual volume (the amount of air left in the lungs after a full breath out), but other lung volumes are usually decreased. The FEV1/FVC ratio is decreased with COPD, meaning a person can't force out much air from their lungs in one second. (Normally someone can expire about 80% of their vital capacity in one second, this is reduced in COPD.)
By far the most common cause of COPD is smoking and approximately 15% of all chronic smokers will develop the disease. Other etiologies inculde alpha-1 anti-trypsin deficency and idiopathic disease.
Treatment includes smoking cessation and bronchodilators. Patients with chronic disease and significant lung function impairment (FEV1 < 50%) may also benefit from the regular use of inhaled steroids.