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Spermidine

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Spermidine
Common name spermidine
Systematic name N-(3-aminopropyl)butane-1,4-diamine
N-(3-aminopropyl)-1,4-diaminobutane
Chemical formula C7H19N3
Chemical structure of spermidine
Disclaimer and references

Spermidine is a polyamine involved in cellular metabolism that can be used to stimulate the enzyme, T7 rna polymerase, a type of RNA polymerase.

Biochemical actions

  • Inhibits neuronal nitric oxide synthase (nNOS).
  • Binds and precipitates DNA.
  • May be used for purification of DNA binding proteins.
  • Stimulates T4 polynucleotide kinase activity.

Properties

  • Molecular Weight: 145.25
  • CAS Number:124-20-9
  • Refractive index: n20/D 1.479(lit.)
  • density: 0.925 g/mL at 25 °C(lit.)
  • Foreign activity: DNase, RNase, and protease, none detected
  • storage temp. 2-8°C

Safety

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

See also