Ethyl dirazepate: Difference between revisions

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+{{Short description|Chemical compound}}
-{{Drugbox|
+{{Drugbox
-|IUPAC_name = ethyl 7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
+| Verifiedfields = changed
-| image=Ethyldirazepate.png
+| verifiedrevid = 373155619
-| width=180
+| IUPAC_name = ethyl 7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
-| CAS_number=23980-14-5
+| image = Ethyl dirazepate.svg
-| ATC_prefix=
+| width = 220
-| ATC_suffix=
-| ATC_supplemental=
+<!--Clinical data-->
-| PubChem=208941
+| tradename =
-| DrugBank=
+| legal_status =
-| C=18 | H=14 | Cl=2 | N=2 | O=3
-| molecular_weight = 377.221
+<!--Pharmacokinetic data-->
+| bioavailability =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
+| CAS_number = 23980-14-5
+| PubChem = 208941
+| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
+| ChemSpiderID = 181035
+| ChEMBL_Ref = {{ebicite|changed|EBI}}
+| ChEMBL = 2106231
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| UNII_Ref = {{fdacite|changed|FDA}}
+| UNII = 74FAA305EW
+<!--Chemical data-->
+| C=18 | H=14 | Cl=2 | N=2 | O=3
 | smiles = CCOC(=O)C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3Cl
+|  StdInChI_Ref = {{stdinchicite|changed|chemspider}}
-| bioavailability=
+| StdInChI = 1S/C18H14Cl2N2O3/c1-2-25-18(24)16-17(23)21-14-8-7-10(19)9-12(14)15(22-16)11-5-3-4-6-13(11)20/h3-9,16H,2H2,1H3,(H,21,23)
-| metabolism =
+|  StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
-| elimination_half-life=
+| StdInChIKey = XFVPZJMXRNBHLQ-UHFFFAOYSA-N
-| excretion =
-| pregnancy_category =
-| legal_status =
-| routes_of_administration=
 }}
-'''Ethyl dirazepate''' is a drug which is a [[benzodiazepine]] derivative which was developed by [[Sanofi Winthrop]]. It has [[anxiolytic]] and [[hypnotic]] and possibly other characteristic benzodiazepine properties.<ref>{{Cite web | url = http://www.psychotropics.dk/moleculeView/default.aspx?ID=1420&Catalogtype=A&ChapterID=1&Thissortorder=17 | title = ethyl dirazepate | accessdate = 7 December 2009 | year = 2003 | publisher = psychotropics.dk }}</ref><ref>{{Cite journal |author= |title=Drugs of the Future |journal=Thomson Reuters |date=November 1981 |volume=6 |issue=11 |url=http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_toc_pr?p_JournalID=2&p_IssueID=140 }}</ref><ref>{{Cite journal |author= |title=LIST OF INTERNATIONAL NON-PROPRIETARY NAMES (INNS), PROVIDED FOR PHARMACEUTICAL SUBSTANCES BY THE WORLD HEALTH ORGANIZATION, WHICH ARE FREE OF DUTY |journal=Official Journal of the European Communities |format=PDF |publisher=eur-lex.europa.eu |date=23 October 2001 |accessdate=7 December 2009 |url=http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2001:279:0767:0876:EN:PDF }}</ref>
+'''Ethyl dirazepate'''<ref>ZA Patent 6804601</ref> is a drug which is a [[benzodiazepine]] derivative which was developed by [[Sanofi Winthrop]]. It has [[anxiolytic]] and [[hypnotic]] and possibly other characteristic benzodiazepine properties.<ref>{{Cite web | url = http://www.psychotropics.dk/moleculeView/default.aspx?ID=1420&Catalogtype=A&ChapterID=1&Thissortorder=17 | title = ethyl dirazepate | access-date = 7 December 2009 | year = 2003 | publisher = psychotropics.dk }}</ref><ref>{{Cite journal |title=Drugs of the Future |journal=Thomson Reuters |date=November 1981 |volume=6 |issue=11 |url=http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_toc_pr?p_JournalID=2&p_IssueID=140 }}</ref><ref>{{Cite journal |title=LIST OF INTERNATIONAL NON-PROPRIETARY NAMES (INNS), PROVIDED FOR PHARMACEUTICAL SUBSTANCES BY THE WORLD HEALTH ORGANIZATION, WHICH ARE FREE OF DUTY |journal=Official Journal of the European Communities |format=PDF |publisher=eur-lex.europa.eu |date=23 October 2001 |access-date=7 December 2009 |url=http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2001:279:0767:0876:EN:PDF |url-status=dead |archive-url=https://archive.today/20140627223035/http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2001:279:0767:0876:EN:PDF |archive-date=27 June 2014 }}</ref>
-{{pharma-stub}}
 ==See also==
@@ Line 32: / Line 47: @@
 {{Benzodiazepines}}
+{{GABAAR PAMs}}
 [[Category:Benzodiazepines]]
-[[Category:Organochlorides]]
+[[Category:Chloroarenes]]
 [[Category:Lactams]]
 [[Category:Ethyl esters]]
-[[Category:Carboxylate esters]]
+[[Category:2-Chlorophenyl compounds]]
+{{sedative-stub}}