Alfa-Metilhistamin

α-Metilhistamin
Nazivi
	IUPAC naziv 1-(3H-Imidazol-4-il)propan-2-amin
	Sistemski IUPAC naziv 1-(1H-Imidazol-4-il)propan-2-amin
Identifikacija
CAS broj	6986-90-9 ; 75614-87-8 (R) ; 75614-93-6 (S) ;
3D model (Jmol)	interaktivna slika; interaktivna slika; interaktivna slika;
ChEBI	CHEBI:295965 ;
ChemSpider	3489 ;
IUPHAR/BPS	1239;
MeSH	Alpha-methylhistamine
PubChem C ID	3615; 156615 (R); 6603865 (S);
	SMILES CC(N)CC1=CNC=N1; CC(CC1=CN=CN1)N; n1cc(nc1)CC(N)C; ; ; ;
Svojstva
Hemijska formula	C6H11N3
Molarna masa	125,18 g·mol−1
log P	-0,346
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	verifikuj (šta je ?)
	Reference infokutije

α-Metilhistamin je histaminski agonist koji je selektivan za histaminski H₃ receptor. On uzrokuje snižavanje krvnog pritiska i usporavanje brzine otkucaja srca u životinjskim modelima.^[4]

Reference

^ Compound Name and Classification^{[мртва веза]}
^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ McLeod, RL; Gertner, SB; Hey, JA (1993). „Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs”. Br J Pharmacol. 110 (2): 553—558. PMC 2175947 . PMID 7902173.

Spoljašnje veze

[1] Compound Name and Classification^{[мртва веза]}

[2] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди

[3] Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.

[4] McLeod, RL; Gertner, SB; Hey, JA (1993). „Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs”. Br J Pharmacol. 110 (2): 553—558. PMC 2175947 . PMID 7902173.

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