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Aftifilinska klatrin -vezujuća kutija Klatrinski kompleks
Simbol Clathrin_bdg
Aftifilin jest protein koji je kod ljudi kodiran genom AFTPH sa hromosoma 3 .[ 5] [ 6] [ 7] [ 8]
Dužina polipeptidnog lanca je 937 aminokiselina , а molekulska težina 102.200 Da .[ 9]
10 20 30 40 50 MEPDIIRMYS SSPPPLDNGA EDDDDDEFGE FGGFSEVSPS GVGFVDFDTP DYTRPKEEFV PSNHFMPIHE FSENVDSLTS FKSIKNGNDK DITAELSAPV KGQSDVLLST TSKEIISSEM LATSIDGMER PGNLNKVVEQ RQNVGTLESF SPGDFRTNMN VVHQNKQLES CNGEKPPCLE ILTNGFAVLE TVNPQGTDDL DNVADSKGRK PLSTHSTEYN LDSVPSPAEE FADFATFSKK ERIQLEEIEC AVLNDREALT IRENNKINRV NELNSVKEVA LGRSLDNKGD TDGEDQVCVS EISIVTNRGF SVEKQGLPTL QQDEFLQSGV QSKAWSLVDS ADNSEAIRRE QCKTEEKLDL LTSKCAHLCM DSVKTSDDEV GSPKEESRKF TNFQSPNIDP TEENDLDDSL SVKNGDSSND FVTCNDINED DFGDFGDFGS ASGSTPPFVT GTQDSMSDAT FEESSEHFPH FSEPGDDFGE FGDINAVSCQ EETILTKSDL KQTSDNLSEE CQLARKSSGT GTEPVAKLKN GQEGEIGHFD SVPNIQDDCN GFQDSDDFAD FSSAGPSQVV DWNAFEDEQK DSCSWAAFGD QQATESHHRK EAWQSHRTDE NIDTPGTPKT HSVPSATSKG AVASGHLQES ATSVQTALLN RLERIFEACF PSILVPDAEE EVTSLKHLLE TSTLPIKTRE ALPESGELLD VWTELQDIHD AHGLRYQWGG SHSNKKLLSS LGIDTRNILF TGNKKQPVIV PMYAAGLGML EPTKEPLKPL SAAEKIASIG QTATMSPDMN TCTSDQFQES LPPVQFDWSS SGLTNPLDAS GGSTLLNLDF FGPVDDSSSS SSTTIPGVDP ELYELTTSKL EISTSSLKVT DAFARLMSTV EKTSTSTSRK PKREEHLSEE AIKVIAGLPD LTFMHAKVLM FPATLTPSTS SQEKADG
Aftifilin formira stabilan kompleks sa p200 i sinerginom gama .[ 6] [ 7] klatrinsku kutiju , sa dva identifikovana klatrin -vezujuća motiva i uključen je u promet vezikula .[ 10] eukariotima .
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