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CYP4X1

From Wikipedia, the free encyclopedia
CYP4X1
Identifiers
AliasesCYP4X1, CYPIVX1, cytochrome P450 family 4 subfamily X member 1
External IDsOMIM: 614999; MGI: 1932403; HomoloGene: 75853; GeneCards: CYP4X1; OMA:CYP4X1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178033
NM_001320289
NM_001320290

NM_001003947

RefSeq (protein)

NP_001307218
NP_001307219
NP_828847

NP_001003947

Location (UCSC)Chr 1: 47.02 – 47.05 MbChr 4: 114.96 – 114.99 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CYP4X1 (cytochrome P450, family 4, subfamily X, polypeptide 1) is a protein which in humans is encoded by the CYP4X1 gene.[5]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.[6]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186377Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047155Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Bylund J; Zhang C; Harder DR (August 2002). "Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain". Biochem. Biophys. Res. Commun. 296 (3): 677–84. doi:10.1016/S0006-291X(02)00918-X. PMID 12176035.
  6. ^ Public Domain This article incorporates public domain material from "Entrez Gene: CYP4X1". Reference Sequence collection. National Center for Biotechnology Information.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.