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Description
Deutsch: Oben: Zellkern eines menschlichen Fibroblasten, in dem alle 24 verschiedenen Chromosomen (1 - 22, X und Y) per Fluoreszenz in situ Hybridisierung (FISH) mit einer unterschiedlichen Kombination von insgesamt 7 Fluorochromen angefärbt wurden. Gezeigt ist eine mittlere Ebene in einem deconvolvierten Bildstapel, der mit Weitfeld-Mikroskopie aufgenommen wurde.
Unten: Falschfarben-Darstellung aller Chromosomenterritorien, die in dieser Fokusebene sichtbar sind, nach Computer-Klassifikation.
English: Top: FISH (Fluorescence in situ hybridization) labeling of all 24 different human chromosomes (1 - 22, X, and Y) in a fibroblast nucleus, each with a different combination of in total seven fluorochromes. Shown is a mid-plane of a deconvoluted image stack which was recorded by wide-field microscopy.
Bottom: False color representation of all chromosome territories visible in this mid-section after computer classification.
Date
Source Bolzer et al., (2005) Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes. PLoS Biol 3(5): e157 DOI: 10.1371/journal.pbio.0030157, part of Figure 1.
Author Andreas Bolzer, Gregor Kreth, Irina Solovei, Daniela Koehler, Kaan Saracoglu, Christine Fauth, Stefan Müller, Roland Eils, Christoph Cremer, Michael R. Speicher, Thomas Cremer
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current20:44, 15 November 2006Thumbnail for version as of 20:44, 15 November 2006439 × 612 (117 KB)Dietzel65{{Information |Description= '''Deutsch''': Oben: Zellkern eines menschlichen Fibroblasten, in dem alle 24 verschiedenen Chromosomen (1­22, X und Y) per Fluoreszenz in situ Hybridisierung mit einer unterschiedlichen Kombination von insgesamt 7 Fluorochro

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