Iduronatna 2-sulfataza
Izgled
(Preusmjereno sa stranice Iduronat-2-sulfataza)
Iduronatna 2-sulfataza | |||||||||
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Iduronatna 2-sulfataza dimer, Human | |||||||||
Identifikatori | |||||||||
EC broj | 3.1.6.13 | ||||||||
CAS broj | 50936-59-9 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Iduronatna 2-sulfataza (EC 3.1.6.13, hondroitinsulfataza, idurono-2-sulfataza, iduronid-2-sulfat sulfataza, L-iduronosulfataza, L-idurono sulfatna sulfataza, iduronatna sulfataza, sulfo-L-iduronatna sulfataza, L-iduronat 2-sulfatna sulfataza, sulfoiduronatna sulfohidrolaza, 2-sulfo-L-iduronat 2-sulfataza, iduronat-2-sulfat sulfataza, iduronat sulfatna sulfataza) je enzim sa sistematskim imenom L-iduronat-2-sulfat 2-sulfohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza 2-sulfatnih grupa L-iduronat 2-sulfatnih jedinica dermatan sulfata, heparan sulfata i heparina
- ↑ Archer, I.M., Harper, P.S. and Wusteman, F.S. (1982). „Multiple forms of iduronate 2-sulphate sulphatase in human tissues and body fluids”. Biochim. Biophys. Acta 708: 134-140. PMID 6816283.
- ↑ Bach, J., Eisenberg, F., Cantz, M. and Neufeld, E.C. (1973). „The defect in the Hunter syndrome: deficiency of sulfoiduronate sulfatase”. Proc. Natl. Acad. Sci. USA 70: 2134-2138. PMID 4269173.
- ↑ DiNatale, P. and Ronsivalle, L. (1981). „Identification and partial characterization of two enzyme forms of iduronate sulfatase from human placenta”. Biochim. Biophys. Acta 661: 106-111. PMID 6945876.
- ↑ Yutaka, T., Fluharty, A.L., Stevens, R.L. and Kihara, H. (1982). „Purification and some properties of human liver iduronate sulfatase”. J. Biochem. (Tokyo) 91: 433-441. PMID 6950934.
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- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
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