Riboflavin kinaza
| Riboflavin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 2.7.1.26 | ||||||||
| CAS broj | 9032-82-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Riboflavin kinaza (EC 2.7.1.26, flavokinaza, FK, RFK) je enzim sa sistematskim imenom ATP:riboflavin 5'-fosfotransferaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + riboflavin ADP + FMN
Kofaktori FMN i FAD učestvuju u brojnim procesima u svim organizmima, uključujući mitohondrijski elektronski transport, fotosintezu, masna-kiselinsku oksidaciju, i metabolizam vitamina B6, vitamina B12 i folata.
- ↑ Chassy, B.M., Arsenis, C. and McCormick, D.B. (1965). „The effect of the length of the side chain of flavins on reactivity with flavokinase”. J. Biol. Chem. 240: 1338-1340. PMID 14284745.
- ↑ Giri, K.V., Krishnaswamy, P.R. and Rao, N.A. (1958). „Studies on plant flavokinase”. Biochem. J. 70: 66-71. PMID 13584303.
- ↑ Kearney, E.B. (1952). „The interaction of yeast flavokinase with riboflavin analogues”. J. Biol. Chem. 194: 747-754. PMID 14927668.
- ↑ McCormick, D.B. and Butler, R.C. (1962). „Substrate specificity of liver flavokinase”. Biochim. Biophys. Acta 65: 326-332.
- ↑ Sandoval, F.J. and Roje, S. (2005). „An FMN hydrolase is fused to a riboflavin kinase homolog in plants”. J. Biol. Chem. 280: 38337-38345. PMID 16183635.
- ↑ Solovieva, I.M., Tarasov, K.V. and Perumov, D.A. (2003). „Main physicochemical features of monofunctional flavokinase from Bacillus subtilis”. Biochemistry (Mosc) 68: 177-181. PMID 12693963.
- ↑ Solovieva, I.M., Kreneva, R.A., Leak, D.J. and Perumov, D.A. (1999). „The ribR gene encodes a monofunctional riboflavin kinase which is involved in regulation of the Bacillus subtilis riboflavin operon”. Microbiology 145: 67-73. PMID 10206712.
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