CDKN2C

CDKN2C
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	1BU9、1G3N、1IHB、1MX2、1MX4、1MX6
识别号
别名	CDKN2C；, INK4C, p18, p18-INK4C, cyclin-dependent kinase inhibitor 2C, cyclin dependent kinase inhibitor 2C
外部ID	OMIM：603369 MGI：105388 HomoloGene：966 GeneCards：CDKN2C
基因位置（人类）
染色体	1号染色体
终止	50,974,634 bp
基因位置（小鼠）
染色体	小鼠4号染色体
终止	109,524,386 bp
RNA表达模式
	; ;
	查阅更多表达数据
基因本体
分子功能	• 血浆蛋白结合; • cyclin-dependent protein serine/threonine kinase inhibitor activity; • protein kinase binding;
细胞组分	• 细胞质; • 细胞质基质; • 细胞核;
生物学过程	• 细胞周期; • regulation of cyclin-dependent protein serine/threonine kinase activity; • oligodendrocyte differentiation; • negative regulation of phosphorylation; • negative regulation of cell growth; • negative regulation of cell population proliferation; • negative regulation of cyclin-dependent protein serine/threonine kinase activity; • G1/S transition of mitotic cell cycle; • negative regulation of G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
直系同源
	1031
	12580
	ENSG00000123080
	ENSMUSG00000028551
	P42773
	Q60772
	NM_078626; NM_001262
	NM_001301368; NM_007671
	NP_001253; NP_523240
	NP_001288297; NP_031697
	维基数据
查看/编辑人类	查看/编辑小鼠

CDKN2C，全称周期蛋白依赖性激酶4抑制蛋白C（英语：Cyclin-dependent kinase 4 inhibitor C），也称为p18蛋白，由人类基因 CDKN2C编码，是周期蛋白依赖性激酶抑制蛋白 INK4家族的一员^[5]^[6]^[7]。

参考文献

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000123080 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000028551 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Guan, K L; Jenkins, C W; Li, Y; Nichols, M A; Wu, X; O'Keefe, C L; Matera, A G; Xiong, Y. Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.. Genes & Development. 1994-12-15, 8 (24). ISSN 0890-9369. doi:10.1101/gad.8.24.2939 （英语）.
^ Blais, Alexandre; Labrie, Yvan; Pouliot, Frédéric; Lachance, Yves; Labrie, Claude. Structure of the Gene Encoding the Human Cyclin-Dependent Kinase Inhibitor p18 and Mutational Analysis in Breast Cancer. Biochemical and Biophysical Research Communications. 1998-06-09, 247 (1). ISSN 0006-291X. doi:10.1006/bbrc.1998.8497 （英语）.
^ Entrez Gene: CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). [2021-08-23]. （原始内容存档于2010-12-05）.