Ergosterol

Ergosterol
	ergosta-5,7,22-trien-3β-ol
Identifikacija
CAS registarski broj	57-87-4
PubChem	444679
ChemSpider	392539
UNII	Z30RAY509F
EINECS broj	200-352-7
MeSH	Ergosterol
ChEBI	16933
ChEMBL	CHEMBL1232562
Jmol-3D slike	Slika 1
SMILES
	O[C@@H]4C/C3=C/C=C1\[C@H](CC[C@]2([C@H]1CC[C@@H]2[C@@H](/C=C/[C@H](C)C(C)C)C)C)[C@@]3(C)CC4
InChI
	InChI=1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1 ; Kod: DNVPQKQSNYMLRS-APGDWVJJSA-N InChI=1/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1; Kod: DNVPQKQSNYMLRS-APGDWVJJBI
Svojstva
Molekulska formula	C28H44O
Molarna masa	396,65 g/mol
Tačka topljenja	160.0 °C
Tačka ključanja	250.0 °C
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Ergosterol (ergosta-5,7,22-trien-3β-ol) je sterol prisutan u gljivicama, i imenovan po ergotu, zajedničkom imenu za članove gljivičnog roda Claviceps iz koga su ergosteroli prvobitno izolovani. Ergosterol se ne javlja u biljnim i životinjskim ćelijama. On je komponenta ćelijske membrane kvasca i gljivica, gde ima istu ulogu kao i holesterol u životinjskim ćelijama.

Ergosterol se javlja u travama poput raži^[5] i lucerke, kao i u cvetajućim biljkama, npr. hmelju.^[6]. Međutim, obično se smatra da je ergosterol detektovan zbog fungalnog rasta na biljkama (kontaminacije), jer glijvice formiraju intergralni deo sistema razlaganja trave. Ergosterolni testovi se mogu koristiti za određivanje fungalnog sadržaja u travi, žitaricama i storčnoj hrani.^[7]^[8].

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Tartaglia LA, Storz G, Brodsky MH, Lai A, Ames BN. (1990-06-25). „Alkyl hydroperoxide reductase from Salmonella typhimurium. Sequence and homology to thioredoxin reductase and other flavoprotein disulfide oxidoreductases”. J Biol Chem. 265: 10535-40.
↑ Magalhães PJ, Carvalho DO, Guido LF, Barros AA. (2007-09-03). „Detection and quantification of provitamin D2 and vitamin D2 in hop (Humulus lupulus L.) by liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry”. J Agric Food Chem 55: 7995-8002.
↑ Steven Y. Newell (2001). „Multiyear patterns of fungal biomass dynamics and productivity within naturally decaying smooth cordgrass shoots”. Limnol. Oceanogr. 46: 573–583. ^{[mrtav link]}
↑ Müller HM, Schwadorf K. (1990). „Ergosterol as a measure for fungal growth in feed. 2. Ergosterol content of mixed feed components and mixed feed”. Arch Tierernahr 40: 385-95.

Vanjske veze

Portal Hemija

Safety (MSDS) data for ergosterol Arhivirano 2007-10-11 na Wayback Machine-u Oxford University (2005)

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[5] Tartaglia LA, Storz G, Brodsky MH, Lai A, Ames BN. (1990-06-25). „Alkyl hydroperoxide reductase from Salmonella typhimurium. Sequence and homology to thioredoxin reductase and other flavoprotein disulfide oxidoreductases”. J Biol Chem. 265: 10535-40.

[6] Magalhães PJ, Carvalho DO, Guido LF, Barros AA. (2007-09-03). „Detection and quantification of provitamin D2 and vitamin D2 in hop (Humulus lupulus L.) by liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry”. J Agric Food Chem 55: 7995-8002.

[7] Steven Y. Newell (2001). „Multiyear patterns of fungal biomass dynamics and productivity within naturally decaying smooth cordgrass shoots”. Limnol. Oceanogr. 46: 573–583. ^{[mrtav link]}

[8] Müller HM, Schwadorf K. (1990). „Ergosterol as a measure for fungal growth in feed. 2. Ergosterol content of mixed feed components and mixed feed”. Arch Tierernahr 40: 385-95.

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