S Wikipedije, slobodne enciklopedije
Protein 1 spermatogenog leucinskog zatvarača jest protein koji je kod ljudi kodiran genom SPZ1 sa hromosoma 5 .
is a protein that in humans is encoded by the [[gen.[ 5] [ 6] [ 7] [ 8] [ 9] [ 10]
Dužina polipeptidnog lanca je 430 aminokiselina , а molekulska težina 49.445 Da .[ 11]
10 20 30 40 50 MASSAKSAEM PTISKTVNPT PDPHQEYLDP RITIALFEIG SHSPSSWGSL PFLKNSSHQV TEQQTAQKFN NLLKEIKDIL KNMAGFEEKI TEAKELFEET NITEDVSAHK ENIRGLDKIN EMLSTNLPVS LAPEKEDNEK KQEMILETNI TEDVSAHKEN IRGLDKINEM LSTNLPVSLA PEKEDNEKKQ QMIMENQNSE NTAQVFARDL VNRLEEKKVL NETQQSQEKA KNRLNVQEET MKIRNNMEQL LQEAEHWSKQ HTELSKLIKS YQKSQKDISE TLGNNGVGFQ TQPNNEVSAK HELEEQVKKL SHDTYSLQLM AALLENECQI LQQRVEILKE LHHQKQGTLQ EKPIQINYKQ DKKNQKPSEA KKVEMYKQNK QAMKGTFWKK DRSCRSLDVC LNKKACNTQF NIHVARKALR GKMRSASSLR
^ a b c GRCh38: Ensembl release 89: ENSG00000164299 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046957 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Hsu SH, Shyu HW, Hsieh-Li HM, Li H (Feb 2001). "Spz1, a novel bHLH-Zip protein, is specifically expressed in testis" . Mech Dev . 100 (2): 177–87. doi :10.1016/S0925-4773(00)00513-X PMID 11165476 . S2CID 17206805 . ^ Sha JH, Zhou ZM, Li JM, Lin M, Zhu H, Zhu H, Zhou YD, Wang LL, Wang YQ, Zhou KY (Jun 2003). "Expression of a novel bHLH-Zip gene in human testis". Asian J Androl . 5 (2): 83–8. PMID 12778315 . ^ Hrabchak C, Varmuza S (Aug 2004). "Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis" . J Biol Chem . 279 (35): 37079–86. doi :10.1074/jbc.M403710200 PMID 15226296 . ^ Horowitz E, Zhang Z, Jones BH, Moss SB, Ho C, Wood JR, Wang X, Sammel MD, Strauss JF 3rd (Apr 2005). "Patterns of expression of sperm flagellar genes: early expression of genes encoding axonemal proteins during the spermatogenic cycle and shared features of promoters of genes encoding central apparatus proteins" . Mol Hum Reprod . 11 (4): 307–17. doi :10.1093/molehr/gah163 PMID 15829580 . ^ Hsu SH, Hsieh-Li HM, Huang HY, Huang PH, Li H (maj 2005). "bHLH-zip transcription factor Spz1 mediates mitogen-activated protein kinase cell proliferation, transformation, and tumorigenesis" . Cancer Res . 65 (10): 4041–50. doi :10.1158/0008-5472.CAN-04-3658 PMID 15899793 . ^ "Entrez Gene: SPZ1 spermatogenic leucine zipper 1" .^ "UniProt, Q9BXG8" (jezik: engleski). Pristupljeno 20. 10. 2021 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Schmutz J, Martin J, Terry A, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 5" (PDF) . Nature . 431 (7006): 268–74. Bibcode :2004Natur.431..268S . doi :10.1038/nature02919 PMID 15372022 . S2CID 4373053 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . 
